Polymerization of actin filaments against membranes produces force for numerous cellular
processes, such as migration, morphogenesis, endocytosis, phagocytosis and organelle …

Filamentous fungi constitute a large group of eukaryotic microorganisms that grow by
forming simple tube-like hyphae that are capable of differentiating into more-complex …

Phagocytosis, the regulated uptake of large particles (> 0.5 μm in diameter), is essential for
tissue homeostasis and is also an early, critical component of the innate immune response …

For over a decade, the actin-related protein 2/3 (ARP2/3) complex, a handful of nucleation-
promoting factors and formins were the only molecules known to directly nucleate actin …

Microtubule nucleation is regulated by the γ-tubulin ring complex (γTuRC) and related γ-
tubulin complexes, providing spatial and temporal control over the initiation of microtubule …

The cellular functions of the actin cytoskeleton require precise regulation of both the
initiation of actin polymerization and the organization of the resulting filaments. The actin …

This review summarizes what is known about the biochemical and biophysical mechanisms
that initiate the assembly of actin filaments in cells. Assembly and disassembly of these …

Formins are a widely expressed family of proteins that govern cell shape, adhesion,
cytokinesis, and morphogenesis by remodeling the actin and microtubule cytoskeletons …

Summary Actin-related protein 2/3 (Arp2/3) complex is a seven-subunit assembly that
nucleates branched actin filaments. Small molecule inhibitors CK-666 and CK-869 bind to …

Endocytosis includes a number of processes by which cells internalize segments of their
plasma membrane, enclosing a wide variety of material from outside the cell. Endocytosis …