The endocannabinoid system and cannabidiol's promise for the treatment of substance use disorder
Substance use disorder is characterized by repeated use of a substance, leading to
clinically significant distress, making it a serious public health concern. The …
clinically significant distress, making it a serious public health concern. The …
Role of cannabidiol in the therapeutic intervention for substance use disorders
F Navarrete, MS García-Gutiérrez… - Frontiers in …, 2021 - frontiersin.org
Drug treatments available for the management of substance use disorders (SUD) present
multiple limitations in efficacy, lack of approved treatments or alarming relapse rates. These …
multiple limitations in efficacy, lack of approved treatments or alarming relapse rates. These …
Cannabidiol attenuates the rewarding effects of cocaine in rats by CB2, 5-HT1A and TRPV1 receptor mechanisms
Cocaine abuse continues to be a serious health problem worldwide. Despite intense
research there is currently no FDA-approved medication to treat cocaine use disorder. The …
research there is currently no FDA-approved medication to treat cocaine use disorder. The …
Cannabidiol and substance use disorder: Dream or reality
S Karimi-Haghighi, Y Razavi, D Iezzi, AF Scheyer… - …, 2022 - Elsevier
Background Cannabidiol (CBD) is one of the major constituents of Cannabis sativa L. that
lacks psychotomimetic and rewarding properties and inhibits the rewarding and reinforcing …
lacks psychotomimetic and rewarding properties and inhibits the rewarding and reinforcing …
Sex differences in the neuropsychiatric effects and pharmacokinetics of cannabidiol: A scoping review
Cannabidiol (CBD) is a non-intoxicating cannabinoid compound with diverse molecular
targets and potential therapeutic effects, including effects relevant to the treatment of …
targets and potential therapeutic effects, including effects relevant to the treatment of …
Cannabidiol in the context of substance use disorder treatment: A systematic review
V Paulus, J Billieux, A Benyamina, L Karila - Addictive behaviors, 2022 - Elsevier
Introduction Cannabidiol (CBD) is a phytocannabinoid found in the Cannabis plant. CBD
has received significant medical attention in relation to its anticonvulsant, anxiolytic, and …
has received significant medical attention in relation to its anticonvulsant, anxiolytic, and …
Cannabidiol treatment might promote resilience to cocaine and methamphetamine use disorders: a review of possible mechanisms
C Calpe-López, MP García-Pardo, MA Aguilar - Molecules, 2019 - mdpi.com
Currently, there are no approved pharmacotherapies for addiction to cocaine and other
psychostimulant drugs. Several studies have proposed that cannabidiol (CBD) could be a …
psychostimulant drugs. Several studies have proposed that cannabidiol (CBD) could be a …
Possible receptor mechanisms underlying cannabidiol effects on addictive-like behaviors in experimental animals
Substance use disorder (SUD) is a serious public health problem worldwide for which
available treatments show limited effectiveness. Since the legalization of cannabis and the …
available treatments show limited effectiveness. Since the legalization of cannabis and the …
Potential of cannabinoid receptor ligands as treatment for substance use disorders
Substance use disorder (SUD) is a major public health crisis worldwide, and effective
treatment options are limited. During the past 2 decades, researchers have investigated the …
treatment options are limited. During the past 2 decades, researchers have investigated the …
Glial cell AMPA receptors in nervous system health, injury and disease
M Ceprian, D Fulton - International journal of molecular sciences, 2019 - mdpi.com
Glia form a central component of the nervous system whose varied activities sustain an
environment that is optimised for healthy development and neuronal function. Alpha-amino …
environment that is optimised for healthy development and neuronal function. Alpha-amino …