Cell surface remodeling by plasmin: a new function for an old enzyme
EI Deryugina, JP Quigley - BioMed Research International, 2012 - Wiley Online Library
Plasmin, one of the most potent and reactive serine proteases, is involved in various
physiological processes, including embryo development, thrombolysis, wound healing and …
physiological processes, including embryo development, thrombolysis, wound healing and …
The role of the plasminogen/plasmin system in inflammation of the oral cavity
T Yatsenko, M Skrypnyk, O Troyanovska, M Tobita… - Cells, 2023 - mdpi.com
The oral cavity is a unique environment that consists of teeth surrounded by periodontal
tissues, oral mucosae with minor salivary glands, and terminal parts of major salivary glands …
tissues, oral mucosae with minor salivary glands, and terminal parts of major salivary glands …
Role of mesenchymal stem cell-derived fibrinolytic factor in tissue regeneration and cancer progression
Tissue regeneration during wound healing or cancer growth and progression depends on
the establishment of a cellular microenvironment. Mesenchymal stem cells (MSC) are part of …
the establishment of a cellular microenvironment. Mesenchymal stem cells (MSC) are part of …
The annexin A2 system and angiogenesis
W Liu, KA Hajjar - Biological chemistry, 2016 - degruyter.com
The formation of new blood vessels from pre-existing vasculature, the process known as
angiogenesis, is highly regulated by pro-and anti-angiogenic signaling molecules including …
angiogenesis, is highly regulated by pro-and anti-angiogenic signaling molecules including …
Inhibition of plasmin protects against colitis in mice by suppressing matrix metalloproteinase 9–mediated cytokine release from myeloid cells
S Munakata, Y Tashiro, C Nishida, A Sato… - Gastroenterology, 2015 - Elsevier
Background & Aims Activated proteases such as plasmin and matrix metalloproteinases
(MMPs) are activated in intestinal tissues of patients with active inflammatory bowel …
(MMPs) are activated in intestinal tissues of patients with active inflammatory bowel …
The multifaceted roles of EGFL7 in cancer and drug resistance
Simple Summary Cancer growth and metastasis require interactions with the extracellular
matrix (ECM), which is home to many biomolecules that support the formation of new …
matrix (ECM), which is home to many biomolecules that support the formation of new …
Inhibition of plasmin attenuates murine acute graft-versus-host disease mortality by suppressing the matrix metalloproteinase-9-dependent inflammatory cytokine …
A Sato, C Nishida, K Sato-Kusubata, M Ishihara… - Leukemia, 2015 - nature.com
The systemic inflammatory response observed during acute graft-versus-host disease
(aGVHD) is driven by proinflammatory cytokines, a 'cytokine storm'. The function of plasmin …
(aGVHD) is driven by proinflammatory cytokines, a 'cytokine storm'. The function of plasmin …
Cancer therapy targeting the fibrinolytic system
The tumor microenvironment is recognized as a key factor in the multiple stages of cancer
progression, mediating local resistance, immune-escape and metastasis. Cancer growth …
progression, mediating local resistance, immune-escape and metastasis. Cancer growth …
The interaction of enolase-1 with caveolae-associated proteins regulates its subcellular localization
D Zakrzewicz, M Didiasova, A Zakrzewicz… - Biochemical …, 2014 - portlandpress.com
Cell-surface-associated proteolysis plays a crucial role in embryonic development,
monocyte/macrophage recruitment and tumour cell invasion. The glycolytic enzyme ENO-1 …
monocyte/macrophage recruitment and tumour cell invasion. The glycolytic enzyme ENO-1 …
Sintered anorganic bone graft increases autocrine expression of VEGF, MMP-2 and MMP-9 during repair of critical-size bone defects
CA Rocha, TM Cestari, HA Vidotti, GF de Assis… - Journal of molecular …, 2014 - Springer
This study aimed to evaluate morphometrically the bone formation and
immunohistochemically the expression of vascular endothelial growth factor (VEGF) and …
immunohistochemically the expression of vascular endothelial growth factor (VEGF) and …