Calpain as a therapeutic target for hypoxic-ischemic encephalopathy
R Zhao, X Teng, Y Yang - Molecular Neurobiology, 2024 - Springer
Hypoxic-ischemic encephalopathy (HIE) is a complex pathophysiological process with
multiple links and factors. It involves the interaction of inflammation, oxidative stress, and …
multiple links and factors. It involves the interaction of inflammation, oxidative stress, and …
PIEZO1 Ion Channel Mediates Ionizing Radiation-Induced Pulmonary Endothelial Cell Ferroptosis via Ca2+/Calpain/VE-Cadherin Signaling
XW Guo, H Zhang, JQ Huang, SN Wang… - Frontiers in molecular …, 2021 - frontiersin.org
Pulmonary endothelial cell dysfunction plays an important role in ionizing radiation (IR)-
induced lung injury. Whether pulmonary endothelial cell ferroptosis occurs after IR and what …
induced lung injury. Whether pulmonary endothelial cell ferroptosis occurs after IR and what …
Calpains as potential therapeutic targets for myocardial hypertrophy
D Aluja, S Delgado-Tomás, M Ruiz-Meana… - International Journal of …, 2022 - mdpi.com
Despite advances in its treatment, heart failure remains a major cause of morbidity and
mortality, evidencing an urgent need for novel mechanism-based targets and strategies …
mortality, evidencing an urgent need for novel mechanism-based targets and strategies …
Targeting the extracellular matrix in traumatic brain injury increases signal generation from an activity-based nanosensor
RM Kandell, JA Kudryashev, EJ Kwon - ACS nano, 2021 - ACS Publications
Traumatic brain injury (TBI) is a critical public health concern and major contributor to death
and long-term disability. After the initial trauma, a sustained secondary injury involving a …
and long-term disability. After the initial trauma, a sustained secondary injury involving a …
Exploratory factor analysis yields grouping of brain injury biomarkers significantly associated with outcomes in neonatal and pediatric ECMO
V Huang, J Roem, DK Ng, J McElrath Schwartz… - Scientific reports, 2024 - nature.com
In this two-center prospective cohort study of children on ECMO, we assessed a panel of
plasma brain injury biomarkers using exploratory factor analysis (EFA) to evaluate their …
plasma brain injury biomarkers using exploratory factor analysis (EFA) to evaluate their …
[HTML][HTML] ALDH2 通过线粒体融合与裂变减轻脂多糖诱导的脑微血管内皮细胞屏障的损伤
王莎莎， 吕恒， 王丽娅， 田美惠， 高洁… - Journal of Southern …, 2022 - ncbi.nlm.nih.gov
ALDH2通过线粒体融合与裂变减轻脂多糖诱导的脑微血管内皮细胞屏障的损伤- PMC Back to
Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage …
Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage …
[HTML][HTML] The effect of calpain inhibitor-I on copper oxide nanoparticle-induced damage and cerebral ischemia-reperfusion in a rat model
This study aimed to investigate the effects of the calpain inhibitor N-Acetyl-Leu-Leu-
norleucinal (ALLN) on neuroapoptotic cell damage caused by Copper Oxide Nanoparticles …
norleucinal (ALLN) on neuroapoptotic cell damage caused by Copper Oxide Nanoparticles …
[HTML][HTML] Efficacy of a cysteine protease inhibitor compared with enalapril in murine heart failure models
D Aluja, S Delgado-Tomás, JA Barrabés, E Miró-Casas… - Iscience, 2024 - cell.com
Cysteine proteases calpains contribute to heart failure (HF), but it remains unknown whether
their inhibition provides any benefit compared to standard pharmacological treatment for HF …
their inhibition provides any benefit compared to standard pharmacological treatment for HF …
[PDF][PDF] Hydroxynonenal makes Alzheimer pathology without amyloid β: Which is a real culprit
T Yamashima - J. Alzheimers. Dis. Park, 2021 - arimatu-clinic.com
Currently, about 50 million people worldwide are suffering from Alzheimer's disease, and
most of the therapeutic drugs including novel antibodies against amyloid β or Tau proteins …
most of the therapeutic drugs including novel antibodies against amyloid β or Tau proteins …
[引用][C] Efficacy of a cysteine protease inhibitor compared with enalapril in murine heart failure models
JA Barrabes, I Song, J Inserte