We performed RNA sequencing on 40,000 cells to create a high-resolution single-cell gene
expression atlas of developing human cortex, providing the first single-cell characterization …

Early mammalian embryogenesis relies on a large range of cellular and molecular
mechanisms to guide cell fate. In this highly complex interacting system, molecular circuitry …

Abstract Development and maintenance of diverse organ systems require context‐specific
regulation of stem cell behaviour. We hypothesize that this is achieved via reciprocal …

Radial glial-like cells (RGLs) in the adult dentate gyrus (DG) function as progenitor cells for
adult hippocampal neurogenesis, a process involved in the stress-related pathophysiology …

During embryonic and adult neurogenesis, neural stem cells (NSCs) generate the correct
number and types of neurons in a temporospatial fashion. Control of NSC activity and fate is …

Neural stem cells are self-renewing, multipotent and undifferentiated precursors that retain
the capacity for differentiation into both glial (astrocytes and oligodendrocytes) and neuronal …

Neural stem cells are able to self-renew and generate glial and neuronal lineages. Neural
stem cell may serve as therapeutic method for neurological disorders including spinal cord …

Although the oscillation and bistability in Notch signaling pathway are essential for neural
development, the precise regulation mechanism and biological significance underlying …

In development, morphogenetic processes are strictly coordinated in time. Cells in a
developing tissue would need mechanisms for time‐keeping. One such time‐keeping …

Recent studies suggest that cells make stochastic choices with respect to differentiation or
division. However, the molecular mechanism underlying such stochasticity is unknown. We …