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Streptococcus pneumoniae (pneumococcus) is a major cause of worldwide mortality and
morbidity, and to a large extent is vaccine-preventable. Nasopharyngeal carriage of …

Background. The frequent lack of a microbiological diagnosis in community-acquired
pneumonia (CAP) impairs pathogen-directed antimicrobial therapy. This study assessed the …

Before 1945, Streptococcus pneumoniae caused more than 90% of cases of pneumonia in
adults. After 1950, the proportion of pneumonia caused by pneumococcus began to decline …

Abstract In 2003 the World Health Organization (WHO) convened a working group and
published a set of standard methods for studies measuring nasopharyngeal carriage of …

Much of the mortality attributed to influenza virus is due to secondary bacterial pneumonia,
particularly from Streptococcus pneumoniae. However, mechanisms underlying this …

Respiratory tract infections are an important cause of morbidity and mortality worldwide.
Chief among these are infections involving the lower airways. The opportunistic bacterial …

INTRODUCTION: Determining the cause of community-acquired pneumonia (CAP) remains
problematic. In this observational study, we systematically applied currently approved …

The genus Streptococcus currently comprises> 100 recognized species, and this number
can certainly be expected to rise with the increasing availability of next‐generation …

Mucosal surfaces of the upper respiratory tract and gut are physiologically colonized with
their own collection of microbes, the microbiota. The normal upper respiratory tract and gut …