Extracellular vesicles (EVs) represent a novel mechanism of intercellular communication as
vehicles for intercellular transfer of functional membrane and cytosolic proteins, lipids, and …

An abundance of evidence shows supporting roles for tetraspanin proteins in human cancer.
Many studies show that the expression of tetraspanins correlates with tumour stage, tumour …

Extracellular vesicles are emerging as a potent mechanism of intercellular communication
because they can systemically exchange genetic and protein material between cells …

Extracellular vesicles (EVs) are membrane-enveloped nanoscale particles that carry various
bioactive signaling molecules secreted by cells. Their biological roles depend on the …

Injection of tumor cells in mice more than 30years ago resulted in the discovery of an
epithelial antigen, later defined as a cell adhesion molecule (EpCAM). Although EpCAM has …

Exosomes are endosomal-derived vesicles, playing a major role in cell-to-cell
communication. Multiple cells secret these vesicles to induce and inhibit different cellular …

Extracellular vesicles (EVs) refer to vesicles that are released by cells into the extracellular
space. EVs mediate cell-to-cell communication via delivery of functional biomolecules …

The tetraspanin CD9 is expressed by all the major subsets of leukocytes (B cells, CD4+ T
cells, CD8+ T cells, natural killer cells, granulocytes, monocytes and macrophages, and …

Lipid rafts are membrane domains, more ordered than the bulk membrane and enriched in
cholesterol and sphingolipids. They represent a platform for protein-lipid and protein–protein …

Tspan8 and CD151 are metastasis-promoting tetraspanins and a knockdown (kd) of Tspan8
or CD151 and most pronounced of both tetraspanins affects the metastatic potential of the …