Bacteriocins targeting Gram-negative phytopathogenic bacteria: Plantibiotics of the future

WM Rooney, R Chai, JJ Milner, D Walker - Frontiers in microbiology, 2020 - frontiersin.org
Gram-negative phytopathogenic bacteria are a significant threat to food crops. These
microbial invaders are responsible for a plethora of plant diseases and can be responsible …

Mechanisms of bacterial immunity, protection, and survival during interbacterial warfare

NW Kennedy, LE Comstock - Cell Host & Microbe, 2024 - cell.com
Most bacteria live in communities, often with closely related strains and species with whom
they must compete for space and resources. Consequently, bacteria have acquired or …

Systematic discovery of pseudomonad genetic factors involved in sensitivity to tailocins

S Carim, AL Azadeh, AE Kazakov, MN Price… - The ISME …, 2021 - academic.oup.com
Tailocins are bactericidal protein complexes produced by a wide variety of bacteria that kill
closely related strains and may play a role in microbial community structure. Thanks to their …

Interspecies killing activity of Pseudomonas syringae tailocins

SL Weaver, L Zhu, S Ravishankar, M Clark… - …, 2022 - microbiologyresearch.org
Tailocins are ribosomally synthesized bacteriocins, encoded by bacterial genomes, but
originally derived from bacteriophage tails. As with both bacteriocins and phage, tailocins …

Genomic Correlates of Tailocin Sensitivity in Pseudomonas syringae

DA Baltrus, S Weaver, L Krings, AE Nguyen - BioRxiv, 2023 - biorxiv.org
Phage derived bacteriocins, also referred to as tailocins, are structures encoded by bacterial
genomes and deployed into the extracellular environment to target and kill sensitive cells …

Prophylactic Application of Tailocins Prevents Infection by Pseudomonas syringae

DA Baltrus, M Clark, KL Hockett, M Mollico… - …, 2022 - Am Phytopath Society
Tailocins are phage-derived bacteriocins that demonstrate great potential as agricultural
antimicrobials given their high killing efficiency and their precise strain-specific targeting …

Heterogenous susceptibility to R-pyocins in populations of Pseudomonas aeruginosa sourced from cystic fibrosis lungs

M Mei, J Thomas, SP Diggle - MBio, 2021 - Am Soc Microbiol
Bacteriocins are proteinaceous antimicrobials produced by bacteria that are active against
other strains of the same species. R-type pyocins are phage tail-like bacteriocins produced …

Variation at the common polysaccharide antigen locus drives lipopolysaccharide diversity within the Pseudomonas syringae species complex

J Jayaraman, WT Jones, D Harvey… - Environmental …, 2020 - Wiley Online Library
The common polysaccharide antigen (CPA) of the lipopolysaccharide (LPS) from
Pseudomonas syringae is highly variable, but the genetic basis for this is poorly understood …

Genome Mining Shows Ubiquitous Presence and Extensive Diversity of Toxin-Antitoxin Systems in Pseudomonas syringae

PP Kandel, M Naumova, C Fautt, RR Patel… - Frontiers in …, 2022 - frontiersin.org
Bacterial toxin-antitoxin (TA) systems consist of two or more adjacent genes, encoding a
toxin and an antitoxin. TA systems are implicated in evolutionary and physiological functions …

Challenges of using protein antibiotics for pathogen control

R Chai, WM Rooney, JJ Milner… - Pest Management …, 2021 - Wiley Online Library
Bacterial phytopathogens represent a significant threat to many economically important
crops. Current control measures often inflict harm on the environment and may ultimately …