Harnessing adipogenesis to prevent obesity

N Haider, L Larose - Adipocyte, 2019 - Taylor & Francis
Obesity and associated metabolic complications, including diabetes, cardiovascular and
hepatic diseases, and certain types of cancers, create a major socioeconomic burden …

[HTML][HTML] Shortcuts to a functional adipose tissue: The role of small non-coding RNAs

BB Brandao, BA Guerra, MA Mori - Redox biology, 2017 - Elsevier
Metabolic diseases such as type 2 diabetes are a major public health issue worldwide.
These diseases are often linked to a dysfunctional adipose tissue. Fat is a large …

FOXO1 regulates the formation of bovine fat by targeting CD36 and STEAP4

Y Song, J Zhang, C Jiang, X Song, H Wu… - International Journal of …, 2023 - Elsevier
Intramuscular fat content is closely related to the quality of beef, where the forkhead box
protein O1 (FOXO1) is involved in adipocyte differentiation and lipid metabolism, but the …

miR-425-5p inhibits differentiation and proliferation in porcine intramuscular preadipocytes

FF Chen, Y Xiong, Y Peng, Y Gao, J Qin… - International Journal of …, 2017 - mdpi.com
Intramuscular fat (IMF) content affects the tenderness, juiciness, and flavor of pork. An
increasing number of studies are focusing on the functions of microRNAs (miRs) during …

Skeletal muscle-derived exosomal miR-146a-5p inhibits adipogenesis by mediating muscle-fat axis and targeting GDF5-PPARγ signaling

M Qin, L Xing, J Wu, S Wen, J Luo, T Chen… - International Journal of …, 2023 - mdpi.com
Skeletal muscle-fat interaction is essential for maintaining organismal energy homeostasis
and managing obesity by secreting cytokines and exosomes, but the role of the latter as a …

[HTML][HTML] Paenibacillus exopolysaccharide repairs GI inflammation by suppressing MAPK and NF-κB and restoring lipid production in Caco-2 cell line

J Zhang, ZQ Li, RJ Zheng, JJ Jiang, DD Li… - Journal of Functional …, 2023 - Elsevier
Paenibacillus polymyxa exopolysaccharide PYQ1-EPS is a homogeneous glucomannan-
type polysaccharide. In this work, its stability and reparative effects on the in vitro model of …

MiR‐127 attenuates adipogenesis by targeting MAPK4 and HOXC6 in porcine adipocytes

Y Gao, Y Wang, X Chen, Y Peng… - Journal of Cellular …, 2019 - Wiley Online Library
MicroRNAs (miRNAs) have critical roles during adipogenesis; however, their precise
functions are not completely understood. Porcine miRNA expression profiles show that miR …

The metabolic syndrome alters the miRNA signature of porcine adipose tissue‐derived mesenchymal stem cells

Y Meng, A Eirin, XY Zhu, H Tang, P Chanana… - Cytometry Part …, 2018 - Wiley Online Library
Autologous transplantation of mesenchymal stem cells (MSCs) is a viable option for the
treatment of several diseases. Evidence indicates that MSCs release extracellular vesicles …

Circulating microRNA levels differ in the early stages of insulin resistance in prepubertal children with obesity

D Santos, P Porter-Gill, G Goode, L Delhey… - Life sciences, 2023 - Elsevier
Aims The increasing prevalence of childhood obesity escalates the risk for related
complications. Circulating microRNAs (miRNAs) have been suggested as good predictive …

miR-429 inhibits differentiation and promotes proliferation in porcine preadipocytes

Y Peng, FF Chen, J Ge, JY Zhu, XE Shi, X Li… - International journal of …, 2016 - mdpi.com
MicroRNAs (miRNAs) are crucial regulatory molecules for adipogenesis. They contribute to
the controlling of proliferation and differentiation of preadipocytes. Previous studies revealed …