With tens of thousands of plant species on earth, we are endowed with an enormous wealth
of medicinal remedies from Mother Nature. Natural products and their derivatives represent …

The global popularity of herbal supplements and the promise they hold in treating various
disease states has caused an unprecedented interest in understanding the molecular basis …

Diabetes is a complex condition with a variety of causes and pathophysiologies. The current
single target approach has not provided ideal clinical outcomes for the treatment of the …

The concomitant use of herbal medicines and pharmacotherapy is wide spread. We have
reviewed the literature to determine the possible interactions between seven popular herbal …

1. P-glycoprotein (P-gp/MDR1), one of the most clinically important transmembrane
transporters in humans, is encoded by the ABCB1/MDR1 gene. Recent insights into the …

ETHNOPHARMACOLOGICAL RELEVANCE: Licorice, one of the oldest and most popular
herbal medicines in the world, has been widely used in traditional Chinese medicine as a …

This article provides an overview of the clinical evidence of interactions between herbal and
conventional medicines. Herbs involved in drug interactions–or that have been evaluated in …

Multidrug resistance (MDR) is regarded as one of the bottlenecks of successful clinical
treatment for numerous chemotherapeutic agents. Multiple key regulators are alleged to be …

St John's wort (SJW) extracts, prepared from the aerial parts of Hypericum perforatum,
contain numerous pharmacologically active ingredients, including naphthodianthrones (eg …

Hypericum perforatum (HP) belongs to the Hypericaceae family and is one of the oldest
used and most extensively investigated medicinal herbs. The medicinal form comprises the …