Bilirubin-induced neurological damage: current and emerging iPSC-derived brain organoid models
AI Pranty, S Shumka, J Adjaye - Cells, 2022 - mdpi.com
Bilirubin-induced neurological damage (BIND) has been a subject of studies for decades,
yet the molecular mechanisms at the core of this damage remain largely unknown …
yet the molecular mechanisms at the core of this damage remain largely unknown …
Global trends in clinical trials involving pluripotent stem cells: a systematic multi-database analysis
J Deinsberger, D Reisinger, B Weber - NPJ Regenerative medicine, 2020 - nature.com
Pluripotent stem cells (PSCs) hold great potential for novel therapeutic approaches to
regenerate or replace functionally impaired tissues. Since the introduction of the induced …
regenerate or replace functionally impaired tissues. Since the introduction of the induced …
Mesenchymal stem cells and tissue bioengineering applications in sheep as ideal model
TDPTP Muniz, MC Rossi… - Stem Cells …, 2024 - Wiley Online Library
The most common technologies in tissue engineering include growth factor therapies; metal
implants, such as titanium; 3D bioprinting; nanoimprinting for ceramic/polymer scaffolds; and …
implants, such as titanium; 3D bioprinting; nanoimprinting for ceramic/polymer scaffolds; and …
Free Bilirubin Induces Neuro-Inflammation in an Induced Pluripotent Stem Cell-Derived Cortical Organoid Model of Crigler-Najjar Syndrome
AI Pranty, W Wruck, J Adjaye - Cells, 2023 - mdpi.com
Bilirubin-induced neurological damage (BIND), which might progress to kernicterus, occurs
as a consequence of defects in the bilirubin conjugation machinery, thus enabling albumin …
as a consequence of defects in the bilirubin conjugation machinery, thus enabling albumin …
Induced pluripotency: a powerful tool for in vitro modeling
R Zahumenska, V Nosal, M Smolar… - International Journal of …, 2020 - mdpi.com
One of the greatest breakthroughs of regenerative medicine in this century was the
discovery of induced pluripotent stem cell (iPSC) technology in 2006 by Shinya Yamanaka …
discovery of induced pluripotent stem cell (iPSC) technology in 2006 by Shinya Yamanaka …
[HTML][HTML] An Overview of Multiple Sclerosis In Vitro Models
J Czpakowska, M Kałuża, P Szpakowski… - International Journal of …, 2024 - mdpi.com
Multiple sclerosis (MS) still poses a challenge in terms of complex etiology, not fully effective
methods of treatment, and lack of healing agents. This neurodegenerative condition …
methods of treatment, and lack of healing agents. This neurodegenerative condition …
Age-associated loss in renal Nestin-positive progenitor cells
MI Buyan, NV Andrianova, VA Popkov… - International Journal of …, 2022 - mdpi.com
The decrease in the number of resident progenitor cells with age was shown for several
organs. Such a loss is associated with a decline in regenerative capacity and a greater …
organs. Such a loss is associated with a decline in regenerative capacity and a greater …
The relationship between mesenchymal stem cells and tumor dormancy
L Zhao, K Zhang, H He, Y Yang, W Li… - Frontiers in cell and …, 2021 - frontiersin.org
Tumor dormancy, a state of tumor, is clinically undetectable and the outgrowth of dormant
tumor cells into overt metastases is responsible for cancer-associated deaths. However, the …
tumor cells into overt metastases is responsible for cancer-associated deaths. However, the …
A comparative study of cell culture conditions during conversion from primed to naive human pluripotent stem cells
I Romayor, L Herrera, M Burón, M Martin-Inaraja… - Biomedicines, 2022 - mdpi.com
The successful reprogramming of human somatic cells into induced pluripotent stem cells
(hiPSCs) represented a turning point in the stem cell research field, owing to their ability to …
(hiPSCs) represented a turning point in the stem cell research field, owing to their ability to …
Pharmacoepigenetic processors: epigenetic drugs, drug resistance, toxicoepigenetics, and nutriepigenetics
R Cacabelos, JC Carril, A Sanmartín, P Cacabelos - Pharmacoepigenetics, 2019 - Elsevier
The pharmacoepigenetic apparatus is integrated by gene clusters of different categories,
including (i) pathogenic genes involved in disease pathogenesis,(ii) mechanistic genes …
including (i) pathogenic genes involved in disease pathogenesis,(ii) mechanistic genes …