[HTML][HTML] Diagnostic and therapeutic potential of extracellular vesicles in B-cell malignancies

E Gargiulo, PE Morande, A Largeot, E Moussay… - Frontiers in …, 2020 - frontiersin.org
Extracellular vesicles (EV), comprising microvesicles and exosomes, are particles released
by every cell of an organism, found in all biological fluids, and commonly involved in cell-to …

Recent advances in extracellular vesicles and their involvements in vasculitis

N Yang, Y Zhao, X Wu, N Zhang, H Song, W Wei… - Free Radical Biology …, 2021 - Elsevier
Systemic vasculitis is a heterogeneous group of multisystem autoimmune disorders
characterized by inflammation of blood vessels. Although many progresses in diagnosis and …

[HTML][HTML] Using genetically modified extracellular vesicles as a non-invasive strategy to evaluate brain-specific cargo

D Rufino-Ramos, S Lule, S Mahjoum, S Ughetto… - Biomaterials, 2022 - Elsevier
The lack of techniques to trace brain cell behavior in vivo hampers the ability to monitor
status of cells in a living brain. Extracellular vesicles (EVs), nanosized membrane …

Engineered extracellular vesicle decoy receptor-mediated modulation of the IL6 trans-signalling pathway in muscle

M Conceição, L Forcina, OPB Wiklander, D Gupta… - Biomaterials, 2021 - Elsevier
Abstract The cytokine interleukin 6 (IL6) is a key mediator of inflammation that contributes to
skeletal muscle pathophysiology. IL6 activates target cells by two main mechanisms, the …

[HTML][HTML] The role of extracellular vesicles in the developing brain: current perspective and promising source of biomarkers and therapy for perinatal brain injury

TKJB Gamage, M Fraser - Frontiers in Neuroscience, 2021 - frontiersin.org
This comprehensive review focuses on our current understanding of the proposed
physiological and pathological functions of extracellular vesicles (EVs) in the developing …

[HTML][HTML] Harnessing EV communication to restore antitumor immunity

C Massaro, W Min, DM Pegtel, SR Baglio - Advanced drug delivery reviews, 2021 - Elsevier
Restoring effective anti-tumor immune responses to cure cancer is a promising strategy, but
challenging to achieve due to the intricate crosstalk between tumor and immune cells. While …