Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics

S Qin, W Xiao, C Zhou, Q Pu, X Deng, L Lan… - Signal transduction and …, 2022 - nature.com
Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen that
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …

Pathogenesis of gram-negative bacteremia

CL Holmes, MT Anderson, HLT Mobley… - Clinical microbiology …, 2021 - Am Soc Microbiol
Gram-negative bacteremia is a devastating public health threat, with high mortality in
vulnerable populations and significant costs to the global economy. Concerningly, rates of …

Revisiting the virulence hallmarks of Pseudomonas aeruginosa: a chronicle through the perspective of quorum sensing

J Chadha, K Harjai, S Chhibber - Environmental microbiology, 2022 - Wiley Online Library
Pseudomonas aeruginosa is an opportunistic pathogen and the leading cause of mortality
among immunocompromised patients in clinical setups. The hallmarks of virulence in P …

Pseudomonas aeruginosa in Chronic Lung Infections: How to Adapt Within the Host?

E Faure, K Kwong, D Nguyen - Frontiers in immunology, 2018 - frontiersin.org
Bacteria that readily adapt to different natural environments, can also exploit this versatility
upon infection of the host to persist. Pseudomonas aeruginosa, a ubiquitous Gram-negative …

The type III secretion system of Pseudomonas aeruginosa: infection by injection

AR Hauser - Nature Reviews Microbiology, 2009 - nature.com
Abstract The Gram-negative bacterium Pseudomonas aeruginosa uses a complex type III
secretion apparatus to inject effector proteins into host cells. The configuration of this …

Antimicrobial mechanisms of phagocytes and bacterial evasion strategies

RS Flannagan, G Cosío, S Grinstein - Nature Reviews Microbiology, 2009 - nature.com
Professional phagocytes have a vast and sophisticated arsenal of microbicidal features.
They are capable of ingesting and destroying invading organisms, and can present …

Pathogenicity islands in bacterial pathogenesis

H Schmidt, M Hensel - Clinical microbiology reviews, 2004 - Am Soc Microbiol
In this review, we focus on a group of mobile genetic elements designated pathogenicity
islands (PAI). These elements play a pivotal role in the virulence of bacterial pathogens of …

[图书][B] Practical handbook of microbiology

LH Green, E Goldman - 2021 - books.google.com
Practical Handbook of Microbiology, 4th edition provides basic, clear and concise
knowledge and practical information about working with microorganisms. Useful to anyone …

[HTML][HTML] Type 3 secretion system of Pseudomonas aeruginosa

G Horna, J Ruiz - Microbiological Research, 2021 - Elsevier
Pseudomonas aeruginosa is an opportunistic pathogen, mainly affecting severe patients,
such as those in intensive care units (ICUs). High levels of antibiotic resistance and a long …

Prevalence of type III secretion genes in clinical and environmental isolates of Pseudomonas aeruginosa

H Feltman, G Schulert, S Khan, M Jain… - …, 2001 - microbiologyresearch.org
The type III secretion system of Pseudomonas aeruginosa transports four known effector
proteins: ExoS, ExoT, ExoU and ExoY. However, the prevalence of the type III secretion …