[HTML][HTML] Adaptive optics imaging of the human retina

SA Burns, AE Elsner, KA Sapoznik, RL Warner… - Progress in retinal and …, 2019 - Elsevier
Adaptive Optics (AO) retinal imaging has provided revolutionary tools to scientists and
clinicians for studying retinal structure and function in the living eye. From animal models to …

Studies of the retinal microcirculation using human donor eyes and high-resolution clinical imaging: insights gained to guide future research in diabetic retinopathy

C Balaratnasingam, D An, M Hein, P Yu… - Progress in Retinal and …, 2023 - Elsevier
The microcirculation plays a key role in delivering oxygen to and removing metabolic wastes
from energy-intensive retinal neurons. Microvascular changes are a hallmark feature of …

Earliest evidence of preclinical diabetic retinopathy revealed using optical coherence tomography angiography perfused capillary density

RB Rosen, JSA Romo, BD Krawitz, S Mo… - American journal of …, 2019 - Elsevier
Purpose To compare perfused capillary density (PCD) in diabetic patients and healthy
controls using optical coherence tomography angiography (OCTA). Methods Forty controls …

Dynamic capillary stalls in reperfused ischemic penumbra contribute to injury: a hyperacute role for neutrophils in persistent traffic jams

ŞE Erdener, J Tang, K Kılıç, D Postnov… - Journal of Cerebral …, 2021 - journals.sagepub.com
Ever since the introduction of thrombolysis and the subsequent expansion of endovascular
treatments for acute ischemic stroke, it remains to be identified why the actual outcomes are …

[HTML][HTML] Progressive retinal neurodegeneration and microvascular change in diabetic retinopathy: longitudinal study using OCT angiography

K Kim, ES Kim, DG Kim, SY Yu - Acta Diabetologica, 2019 - Springer
Aims To investigate the association between progressive macular ganglion cell/inner
plexiform layer (mGCIPL) thinning and change of optical coherence tomography …

Imaging the retinal vasculature

SA Burns, AE Elsner, TJ Gast - Annual review of vision science, 2021 - annualreviews.org
Advances in retinal imaging are enabling researchers and clinicians to make precise
noninvasive measurements of the retinal vasculature in vivo. This includes measurements of …

[HTML][HTML] Parafoveal nonperfusion analysis in diabetic retinopathy using optical coherence tomography angiography

BD Krawitz, E Phillips, RD Bavier, S Mo… - … Vision Science & …, 2018 - iovs.arvojournals.org
Purpose: To describe a new technique for mapping parafoveal intercapillary areas (PICAs)
using optical coherence tomography angiography (OCTA), and demonstrate its utility for …

Protective effect of PACAP-38 on retinal pigmented epithelium in an in vitro and in vivo model of diabetic retinopathy through EGFR-dependent mechanism

G Maugeri, AG D'Amico, C Bucolo, V D'Agata - Peptides, 2019 - Elsevier
Diabetic retinopathy (DR) is one of the most common microvascular complications of
diabetes. In the last years, several in vivo studies have demonstrated the protective role of …

Modeling of xenobiotic transport and metabolism in virtual hepatic lobule models

X Fu, JP Sluka, SG Clendenon, KW Dunn, Z Wang… - PLoS one, 2018 - journals.plos.org
Computational models of normal liver function and xenobiotic induced liver damage are
increasingly being used to interpret in vitro and in vivo data and as an approach to the de …

Microvascular basis of cognitive impairment in type 1 diabetes

S Sharma, CE Brown - Pharmacology & Therapeutics, 2022 - Elsevier
The complex computations of the brain require a constant supply of blood flow to meet its
immense metabolic needs. Perturbations in blood supply, even in the smallest vascular …