BACKGROUND: Photodynamic therapy (PDT) is an established, minimally invasive
treatment for specific types of cancer. During PDT, reactive oxygen species (ROS) are …

The cancer incidence world-wide has caused an increase in the demand for effective forms
of treatment. One unconventional form of treatment for cancer is photodynamic therapy …

Developing non‐cationic gene carriers and achieving efficient endo/lysosome escape of
functional nucleic acids in cytosol are two major challenges faced by the field of gene …

Photodynamic therapy (PDT) is an approved modality for the treatment of various types of
maligancies and diseased states. However, most of the available photosensitizers (PS) are …

Singlet oxygen (1O2) is the excited state of ground, triplet state, molecular oxygen (O2).
Photosensitized 1O2 has been extensively studied as one of the reactive oxygen species …

Hypoxia has been identified as one of the hallmarks of tumor environments and a prognosis
factor in many cancers. The development of ideal chemical probes for imaging and sensing …

Photodynamic therapy is an emerging noninvasive cancer treatment approach, which
requires a photosensitizer (PS), light, and molecular oxygen. In this study, we have …

Endosomal escape in cell-penetrating peptide (CPP)-based drug/macromolecule delivery
systems is frequently insufficient. The CPP-fused molecules tend to remain trapped inside …

Detection of singlet oxygen is of great importance for a range of therapeutic applications,
particularly photodynamic therapy, plasma therapy and also during photo-endosomolytic …

In this study we explored the efficacy of combining low dose photodynamic therapy using a
porphyrin photosensitiser and dactinomycin, a commonly used chemotherapeutic agent …