The evolution of polyurethane heart valve replacements: How chemistry translates to the clinic

M Crago, A Lee, S Farajikhah, F Oveissi… - Materials Today …, 2022 - Elsevier
Current heart valve replacements (HVRs) fail to comprehensively capture the physiological
behavior of native heart valve tissues, allowing the burden of valvular heart disease to …

HPC+ in the medical field: Overview and current examples

M Koch, C Arlandini, G Antonopoulos… - … and Health Care, 2023 - content.iospress.com
BACKGROUND: To say data is revolutionising the medical sector would be a vast
understatement. The amount of medical data available today is unprecedented and has the …

A high-throughput hybrid task and data parallel Poisson solver for large-scale simulations of incompressible turbulent flows on distributed GPUs

H Zolfaghari, D Obrist - Journal of Computational Physics, 2021 - Elsevier
The solution of the pressure Poisson equation arising in the numerical solution of
incompressible Navier–Stokes equations (INSE) is by far the most expensive part of the …

Sensitivity and downstream influence of the impinging leading-edge vortex instability in a bileaflet mechanical heart valve

H Zolfaghari, RR Kerswell, D Obrist… - Journal of Fluid …, 2022 - cambridge.org
Bileaflet mechanical heart valves (BMHV) create unphysiological turbulent flow. Such
turbulent flow involves multiple instability mechanisms interacting with one another in a …

Instability mechanisms initiating laminar–turbulent transition past bioprosthetic aortic valves

KM Bornemann, D Obrist - Journal of Fluid Mechanics, 2024 - cambridge.org
Bioprosthetic heart valves create turbulent flow during early systole which might be
detrimental to their durability and performance. Complex mechanisms in the unsteady and …

Impact of superhydrophobicity on the fluid dynamics of a bileaflet mechanical heart valve

H Hatoum, S Vallabhuneni, AK Kota, DL Bark… - journal of the …, 2020 - Elsevier
Objective The objective of this study is to evaluate the impact of superhydrophobic coating
on the hemodynamics and turbulence characteristics of a bileaflet mechanical valve in the …

Wall shear stress and pressure patterns in aortic stenosis patients with and without aortic dilation captured by high-performance image-based computational fluid …

H Zolfaghari, M Andiapen, A Baumbach… - PLOS Computational …, 2023 - journals.plos.org
Spatial patterns of elevated wall shear stress and pressure due to blood flow past aortic
stenosis (AS) are studied using GPU-accelerated patient-specific computational fluid …

Statistical characteristics of flow field through open and semi-closed bileaflet mechanical heart valve

O Voskoboinyk, L Tereshchenko… - SciMedicine …, 2020 - scimedjournal.org
The formation of thrombi on the streamlined surface of the bileaflet mechanical heart valves
is one of the main disadvantages of such valves. Thrombi block the valve leaflets and disrupt …

Peak Flow in Model Aorta Through Bi-Leaflet Mechanical Heart Valve with Varying Orientation

KH Satheesh, SD Sharma - ASAIO Journal, 2021 - journals.lww.com
This study aims to numerically investigate the effect of bi-leaflet mechanical heart valve
(BMHV) orientation on flow pattern in a realistic human aorta model with branches. The …

[PDF][PDF] SciMedicine Journal

SCBMH Valve - academia.edu
The formation of thrombi on the streamlined surface of the bileaflet mechanical heart valves
is one of the main disadvantages of such valves. Thrombi block the valve leaflets and disrupt …