Homochiral catalysts that can effect asymmetric transformations are invaluable in the
production of optically active molecules. Researchers are actively pursuing the design of …

Abstract The legacy of Gilbert Newton Lewis (1875–1946) pervades the lexicon of chemical
bonding and reactivity. The power of his concept of donor–acceptor bonding is evident in the …

The enantioselective production of compounds is a central theme in current research. The
broad utility of synthetic chiral molecules as single-enantiomer pharmaceuticals, in …

Abstract Das Erbe von Gilbert Newton Lewis (1875–1946) ist im Wörterbuch der
chemischen Bindung und Reaktivität allgegenwärtig. Die Bedeutung seines Konzepts der …

A novel concept that conversion of chiral 2-substituted DMAP into its DMAP-N-oxide could
significantly enhance the catalytic activity and still be used as an acyl transfer catalyst is …

Stereoselective allylations of carbonyl compounds such as aldehydes and ketones are
useful but challenging reactions in organic chemistry. The resulting chiral secondary and …

Reliable, selective and environmentally friendly chemical transformations are crucial to the
development of new therapeutics and the design of novel materials. Chiral catalysts that can …

Bifunctional catalysts bearing amino and urea functional groups have been applied for a
novel, highly enantioselective synthesis of axially chiral isoquinoline N-oxides, which are …

The design and synthesis of new chiral Lewis bases is a field of extraordinary activity; in this
context, while N-oxides derived from both N-heterocyclic systems and aliphatic amines have …

An efficient chiral 4-aryl-pyridine-N-oxide (ArPNO) nucleophilic organocatalyst was
rationally designed, synthesized, and applied to the acylative dynamic kinetic resolution of …