[HTML][HTML] Contribution of neutrophils to acute lung injury

J Grommes, O Soehnlein - Molecular medicine, 2011 - Springer
Abstract Treatment of acute lung injury (ALI) and its most severe form, acute respiratory
distress syndrome (ARDS), remain unsolved problems of intensive care medicine …

Heparin‐binding protein: a key player in the pathophysiology of organ dysfunction in sepsis

J Fisher, A Linder - Journal of Internal Medicine, 2017 - Wiley Online Library
Infectious diseases remain a major health problem, and sepsis and other severe infectious
diseases are common causes of morbidity and mortality. There is a need for clinical and …

A promising candidate: heparin‐binding protein steps onto the stage of sepsis prediction

Y Yang, G Liu, Q He, J Shen, L Xu… - Journal of …, 2019 - Wiley Online Library
Sepsis is a systemic inflammatory response syndrome caused by infection. With high
morbidity and mortality of this disease, there is a need to find early effective diagnosis and …

Characterization of the human neutrophil alloantigen-3a

A Greinacher, J Wesche, E Hammer, B Fürll, U Völker… - Nature medicine, 2010 - nature.com
Transfusion-related acute lung injury (TRALI) is a frequent cause of transfusion-associated
morbidity and mortality. Severe TRALI is often due to antibodies in blood components …

Mitochondrial damage‐associated molecular patterns as potential proinflammatory mediators in post–platelet transfusion adverse effects

K Yasui, N Matsuyama, A Kuroishi, Y Tani… - …, 2016 - Wiley Online Library
BACKGROUND Platelet concentrates (PCs) are the most common blood components
eliciting nonhemolytic transfusion reactions (NHTRs), such as allergic transfusion reactions …

[HTML][HTML] Increased plasma levels of heparin-binding protein in patients with acute respiratory distress syndrome

Q Lin, J Shen, L Shen, Z Zhang, F Fu - Critical care, 2013 - Springer
Introduction Heparin-binding protein (HBP) is an antimicrobial protein stored in neutrophil
granules and plays a role in endothelial permeability regulation. The aim was to assess the …

Heparin‐binding protein as a biomarker of post‐injury sepsis in trauma patients

HD Halldorsdottir, J Eriksson… - Acta …, 2018 - Wiley Online Library
Background Heparin‐binding protein (HBP) is a neutrophil‐derived protein advocated as a
biomarker in sepsis. We evaluated plasma HBP as a predictor of post‐injury sepsis in …

The role of β2 integrin associated heparin-binding protein release in ARDS

Y Liu, S Ma, X Wang, Y Feng, S Zhang, S Wang… - Life Sciences, 2018 - Elsevier
Aims PMNs (polymorphonuclear neutrophil) play important roles in early stage of
inflammation induced ARDS (Acute Respiratory Distress Syndrome). Both HBP (Heparin …

Recent advances in laboratory assays for nonhemolytic transfusion reactions

F Hirayama - Transfusion, 2010 - Wiley Online Library
Nonhemolytic transfusion reactions (NHTRs) are the most common transfusion reactions
and include transfusion‐related acute lung injury (TRALI) and allergic and febrile reactions …

TRALI–new challenges for histocompatibility and immunogenetics in transfusion medicine

BK Flesch, EK Petershofen, J Bux - Tissue Antigens, 2011 - Wiley Online Library
Antibodies against human leukocyte antigens (HLAs) have long been associated with
transfusion‐related acute lung injury (TRALI). In contrast to febrile transfusion reactions and …