The hematologist and radiation casualties
N Dainiak, JK Waselenko, JO Armitage… - ASH Education …, 2003 - ashpublications.org
Since the terrorist attack of September 11, 2001, preparation by the health care system for
an act of terrorism has been mandated by leaders of governments. Scenarios for terrorist …
an act of terrorism has been mandated by leaders of governments. Scenarios for terrorist …
IL-7 and IL-15: therapeutic cytokines for immunodeficiency
Ö Alpdogan, MRM van den Brink - Trends in immunology, 2005 - cell.com
Immunodeficiency due to inborn errors, infections, autoimmune diseases and the toxicity of
certain therapies, has become an important clinical challenge. Strategies to enhance …
certain therapies, has become an important clinical challenge. Strategies to enhance …
Intratumoral expression of IL-7 and IL-12 using an oncolytic virus increases systemic sensitivity to immune checkpoint blockade
S Nakao, Y Arai, M Tasaki, M Yamashita… - Science translational …, 2020 - science.org
The immune status of the tumor microenvironment is a key indicator in determining the
antitumor effectiveness of immunotherapies. Data support the role of activation and …
antitumor effectiveness of immunotherapies. Data support the role of activation and …
Expression and function of the interleukin 7 receptor in murine lymphocytes.
T Sudo, S Nishikawa, N Ohno… - Proceedings of the …, 1993 - National Acad Sciences
A monoclonal antibody, A7R34, that recognizes the high-affinity interleukin 7 receptor (IL-
7Ra) and blocks the binding between IL-7 and IL-7Ra has been produced. Cell surface …
7Ra) and blocks the binding between IL-7 and IL-7Ra has been produced. Cell surface …
Long-acting recombinant human interleukin-7, NT-I7, increases cytotoxic CD8 T cells and enhances survival in mouse glioma models
Purpose: Patients with glioblastoma (GBM) are treated with radiotherapy (RT) and
temozolomide (TMZ). These treatments may cause prolonged systemic lymphopenia, which …
temozolomide (TMZ). These treatments may cause prolonged systemic lymphopenia, which …
Administration of interleukin-7 after allogeneic bone marrow transplantation improves immune reconstitution without aggravating graft-versus-host disease
O Alpdogan, C Schmaltz, SJ Muriglan… - Blood, The Journal …, 2001 - ashpublications.org
Prolonged immunodeficiency after allogeneic bone marrow transplantation (BMT) causes
significant morbidity and mortality from infection. This study examined in murine models the …
significant morbidity and mortality from infection. This study examined in murine models the …
IL-7 administration alters the CD4: CD8 ratio, increases T cell numbers, and increases T cell function in the absence of activation
LA Geiselhart, CA Humphries, TA Gregorio… - The Journal of …, 2001 - journals.aai.org
IL-7 is vital for the development of the immune system and profoundly enhances the function
of mature T cells. Chronic administration of IL-7 to mice markedly increases T cell numbers …
of mature T cells. Chronic administration of IL-7 to mice markedly increases T cell numbers …
[HTML][HTML] Emerging concepts in myeloid cell biology after spinal cord injury
AL Hawthorne, PG Popovich - Neurotherapeutics, 2011 - Elsevier
Traumatic spinal cord injury (SCI) affects the activation, migration, and function of microglia,
neutrophils and monocyte/macrophages. Because these myeloid cells can positively and …
neutrophils and monocyte/macrophages. Because these myeloid cells can positively and …
Radiation therapy and immunotherapy: what is the optimal timing or sequencing?
ML Aliru, JE Schoenhals, BP Venkatesulu… - …, 2018 - Taylor & Francis
Radiotherapy is a component of the standard of care for many patients with locally advanced
nonmetastatic tumors and increasingly those with oligometastatic tumors. Despite …
nonmetastatic tumors and increasingly those with oligometastatic tumors. Despite …
Megakaryocyte growth and development factor ameliorates carboplatin-induced thrombocytopenia in mice
TR Ulich, J del Castillo, S Yin, S Swift, D Padilla… - 1995 - ashpublications.org
Megakaryocyte growth and development factor (MGDF) administered intraperitoneally (IP) to
mice causes a dose-dependent thrombocytosis accompanied by a decrease in mean …
mice causes a dose-dependent thrombocytosis accompanied by a decrease in mean …