Mechanobiological approaches for stimulating chondrogenesis of stem cells

M Volz, KR Wyse-Sookoo, F Travascio… - Stem cells and …, 2022 - liebertpub.com
Chondrogenesis is the process of differentiation of stem cells into mature chondrocytes.
Such a process consists of chemical, functional, and structural changes which are initiated …

Super‐Strong Hydrogel Composites Reinforced with PBO Nanofibers for Cartilage Replacement

AS Oliveira, JC Silva, MV Loureiro… - Macromolecular …, 2023 - Wiley Online Library
Cartilage replacement materials exhibiting a set of demanding properties such as high water
content, high mechanical stiffness, low friction, and excellent biocompatibility are quite …

Chondrogenic differentiation of mesenchymal stem/stromal cells on 3D porous poly (ε-caprolactone) scaffolds: Effects of material alkaline treatment and chondroitin …

CS Moura, JC Silva, S Faria, PR Fernandes… - Journal of bioscience …, 2020 - Elsevier
Cartilage defects resultant from trauma or degenerative diseases (eg, osteoarthritis) can
potentially be repaired using tissue engineering (TE) strategies combining progenitor cells …

A novel approach for design and manufacturing of curvature-featuring scaffolds for osteochondral repair

P Marcelino, JC Silva, CS Moura, J Meneses… - Polymers, 2023 - mdpi.com
Osteochondral (OC) defects affect both articular cartilage and the underlying subchondral
bone. Due to limitations in the cartilage tissue's self-healing capabilities, OC defects exhibit …

Development of a novel feeding regime for large scale production of human umbilical cord mesenchymal stem/stromal cells

Y Dai, X Cui, G Zhang, A Mohsin, H Xu, Y Zhuang… - Cytotechnology, 2022 - Springer
Human umbilical cord mesenchymal stem/stromal cells (hUC-MSCs) have attracted
significant research interests in regenerative medicine and cell-based therapies due to their …

Evaluation of rabbit adipose derived stem cells fate in perfused multilayered silk fibroin composite scaffold for Osteochondral repair

S Zadegan, B Vahidi… - … Research Part B …, 2024 - Wiley Online Library
Abstract Development of osteochondral tissue engineering approaches using scaffolds
seeded with stem cells in association with mechanical stimulations has been recently …

Role of mechanical signals in articular cartilage tissue regeneration: a review

M Shokrollahlahi, HM Aznaveh… - … Journal of Nano …, 2023 - inderscienceonline.com
Articular cartilage (AC) is a kind of connective tissue that wraps the surfaces of long bones in
diarthrodial joints and serves a vital function in the human body. Damaged cartilage has low …

Generation of chondroinductive scaffolds with improved biomechanical properties and development of a bioreactor for cartilage tissue engineering

D Martínez Moreno - 2023 - digibug.ugr.es
Osteoarthritis (OA) is a sizeable socioeconomic condition mainly affecting articular cartilage,
a tissue with limited self-healing potential and hence a suitable target for regenerative …

Экспериментальные подходы к регенерации и тканевой инженерии суставного хряща с использованием клеточно-инженерных конструкций

ЮБ Басок - 2021 - elibrary.ru
Объект исследования: суставной хрящ свиньи, коллагенсодержащий гидрогель,
мезенхимальные стромальные клетки человека из жировой ткани, пуповины, пульпы …

Design and numerical simulation characterisation of additively manufactured bioreactors for tissue engineering applications

K Chaplin - 2022 - repository.lboro.ac.uk
Tissue engineered constructs have great potential in creating representative models of
physiology and disease for research and pharmaceutical screening. Dense, mature …