Juvenile idiopathic arthritis (JIA) is the most common chronic inflammatory arthropathy of
childhood. Juvenile idiopathic arthritis is believed to be a complex genetic trait influenced by …

Lymphocyte activation must be tightly regulated to ensure sufficient immunity to pathogens
and prevent autoimmunity. Protein tyrosine phosphatases (PTPs) serve critical roles in this …

We used the Immunochip array to analyze 2,816 individuals with juvenile idiopathic arthritis
(JIA), comprising the most common subtypes (oligoarticular and rheumatoid factor–negative …

Rheumatoid arthritis (RA) is an autoimmune disease characterized by infiltration of immune
cells in the synovium. However, the crosstalk of immune cells and synovial fibroblasts is still …

Recent advances in the identification of susceptibility genes and environmental exposures
provide broad support for a post-infectious autoimmune basis for narcolepsy/hypocretin …

In spite of the well-known clustering of multiple autoimmune disorders in families, analyses
of specific shared genes and polymorphisms between systemic lupus erythematosus (SLE) …

Most of the recently identified autoimmunity loci are shared among multiple autoimmune
diseases. The pattern of genetic association with autoimmune phenotypes varies …

Objectives Juvenile idiopathic arthritis (JIA) is the most prevalent form of juvenile rheumatic
disease. Our understanding of the genetic risk factors for this disease is limited due to low …

Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in the
paediatric population. JIA comprises a heterogeneous group of disorders with different onset …

Over the years, the commonly used term to describe juvenile idiopathic arthritis (JIA) has
changed. By definition, JIA includes all types of arthritis with no apparent cause, lasting more …