Although deficiencies in polyphenol intake do not result in specific deficiency diseases,
adequate intake of polyphenols could confer health benefits, especially with regard to …

Diabetes mellitus type 2 (T2DM) is a metabolic disorder develops due to the overproduction
of free radicals where oxidative stress could contribute it. Possible factors are defective …

Diabetes mellitus (DM) is a metabolic diseases characterized by hyperglycemia due to
insufficient or inefficient insulin secretory response. This chronic disease is a global problem …

Diet-induced obesity is associated with low-grade inflammation, which, in most cases, leads
to the development of metabolic disorders, primarily insulin resistance and type 2 diabetes …

Increased permeability of the intestinal barrier is proposed as an underlying factor for
obesity-associated pathologies. Consumption of high fat diets (HFD) is associated with …

Insulin resistance (IR) is apparent when tissues responsible for clearing glucose from the
blood, such as adipose and muscle, do not respond properly to appropriate signals. IR is …

Obesity is characterized by a state of chronic inflammation in adipose tissue mediated by the
secretion of a range of inflammatory cytokines. In comparison to WAT, relatively little is …

Epicatechin (EC) is a flavanol easily obtained through the diet and is present in tea, cocoa,
vegetables, fruits, and cereals. Recent studies have shown that EC protects human health …

Objective In the wake of intracerebral hemorrhage (ICH), a devastating stroke with no
effective treatment, hemoglobin/iron‐induced oxidative injury leads to neuronal loss and …

Insulin resistance is the primary characteristic of type 2 diabetes. Cocoa and its main
flavanol,(−)-epicatechin (EC), display some antidiabetic effects, but the mechanisms for their …