Prognostic value of increased integrin-beta 1 expression in solid cancers: a meta-analysis

Q Sun, C Zhou, R Ma, Q Guo, H Huang… - OncoTargets and …, 2018 - Taylor & Francis
Integrin-beta 1 (ITGB1) is aberrantly overexpressed or downregulated in solid cancers;
however, its prognostic value remains controversial. Therefore, we conducted a meta …

Thymoquinone inhibits proliferation and migration of MDA-MB-231 triple negative breast cancer cells by suppressing autophagy, Beclin-1 and LC3

TD Ünal, Z Hamurcu, N Delibaşı, V Çınar… - Anti-Cancer Agents …, 2021 - ingentaconnect.com
Background: Triple Negative Breast Cancer (TNBC) is an aggressive and highly
heterogeneous subtype of breast cancer associated with poor prognosis. A better …

Biomimetic nanovesicles made from iPS cell-derived mesenchymal stem cells for targeted therapy of triple-negative breast cancer

Q Zhao, B Hai, X Zhang, J Xu, B Koehler… - … , Biology and Medicine, 2020 - Elsevier
Nanoparticles made from membrane of mesenchymal stem cells (MSCs) showed active
targeting capacities to prostate and lung cancers, but further studies are hindered by limited …

[HTML][HTML] Invasive phenotype in triple negative breast cancer is inhibited by blocking SIN3A–PF1 interaction through KLF9 mediated repression of ITGA6 and ITGB1

R Kadamb, BA Leibovitch, EF Farias, N Dahiya… - Translational …, 2022 - Elsevier
SIN3A, a scaffold protein has regulatory functions in tumor biology. Through its Paired
amphipathic helix (PAH2) domain, SIN3A interacts with PHF12 (PF1), a protein with SIN3 …

Transcriptomic analysis reveals high ITGB1 expression as a predictor for poor prognosis of pancreatic cancer

Y Iwatate, H Yokota, I Hoshino, F Ishige, N Kuwayama… - PLoS …, 2022 - journals.plos.org
Transcriptomic analysis of cancer samples helps identify the mechanism and molecular
markers of cancer. However, transcriptomic analyses of pancreatic cancer from the …

The Breast Cancer Single-Cell Atlas: Defining cellular heterogeneity within model cell lines and primary tumors to inform disease subtype, stemness, and treatment …

A Dave, D Charytonowicz, NJ Francoeur, M Beaumont… - Cellular Oncology, 2023 - Springer
Abstract Purpose Breast Cancer (BC) is the most diagnosed cancer in women; however,
through significant research, relative survival rates have significantly improved. Despite …

Long-term simulation of microgravity induces changes in gene expression in breast cancer cells

J Sahana, JL Cortés-Sánchez, V Sandt… - International Journal of …, 2023 - mdpi.com
Microgravity changes the gene expression pattern in various cell types. This study focuses
on the breast cancer cell lines MCF-7 (less invasive) and MDA-MB-231 (triple-negative …

Prognostic signature associated with radioresistance in head and neck cancer via transcriptomic and bioinformatic analyses

GR You, AJ Cheng, LY Lee, YC Huang, H Liu, YJ Chen… - BMC cancer, 2019 - Springer
Background Radiotherapy is an indispensable treatment modality in head and neck cancer
(HNC), while radioresistance is the major cause of treatment failure. The aim of this study is …

β1 integrin as a prognostic and predictive marker in triple-negative breast cancer

HL Yin, CC Wu, CH Lin, CY Chai, MF Hou… - International journal of …, 2016 - mdpi.com
Triple negative breast cancer (TNBC) displays higher risk of recurrence and distant
metastasis. Due to absence of estrogen receptor (ER), progesterone receptor (PR) and …

Integrin β1 in breast cancer: mechanisms of progression and therapy

Q Huang, J Wang, H Ning, W Liu, X Han - Breast Cancer, 2024 - Springer
The therapy for breast cancer (BC), to date, still needs improvement. Apart from traditional
therapy methods, biological therapy being explored opens up a novel avenue for BC …