Therapeutic potential of certain terpenoids as anticancer agents: a scoping review

S Kamran, A Sinniah, MAM Abdulghani, MA Alshawsh - Cancers, 2022 - mdpi.com
Simple Summary Terpenoids are bioactive compounds with a variety of pharmacological
activities, including anticancer activity. This review paper aimed to focus on the anticancer …

Nutritional Value and Preventive Role of Nigella sativa L. and Its Main Component Thymoquinone in Cancer: An Evidenced-Based Review of Preclinical and Clinical …

J Ansary, F Giampieri, TY Forbes-Hernandez, L Regolo… - Molecules, 2021 - mdpi.com
In recent times, scientific attention has been paid to different foods and their bioactive
components for the ability to inhibit the onset and progress of different types of cancer …

Thymoquinone synergizes gemcitabine anti-breast cancer activity via modulating its apoptotic and autophagic activities

HA Bashmail, AA Alamoudi, A Noorwali, GA Hegazy… - Scientific reports, 2018 - nature.com
The use of anti-cancer adjuvant therapy is rationalized by potentiating the efficacy, and/or
protecting from major side effects of chemotherapeutics. Thymoquinone (TQ) is a naturally …

Thymoquinone‐induced antitumor and apoptosis in human lung adenocarcinoma cells

S Samarghandian, M Azimi‐Nezhad… - Journal of cellular …, 2019 - Wiley Online Library
Background Lung cancer has been associated with the highest cancer‐associated mortality
rate in the world. Chemotherapeutic management of cancer necessitates introducing new …

Thymoquinone and quercetin induce enhanced apoptosis in non‐small cell lung cancer in combination through the Bax/Bcl2 cascade

S Alam, T Mohammad, RA Padder… - Journal of Cellular …, 2022 - Wiley Online Library
The treatments available for non‐small cell lung cancer exert various side effects in patients,
and the burden of treatment cost is high. Therefore, exploring the alternative system of …

Exploring the potential of bioactive compounds in preventing cancer growth and progression: A comprehensive review

M Foroughi-Gilvaee, D Martirosyan… - Bioactive Compounds in …, 2024 - ffhdj.com
Cancer stands as a prominent global cause of mortality, with a noteworthy surge in related
deaths in recent years. Over the past decade, several bioactive compounds have emerged …

Therapeutic perspective of thymoquinone: A mechanistic treatise

MS Butt, M Imran, A Imran, MS Arshad… - Food Science & …, 2021 - Wiley Online Library
The higher utilization of fruits and vegetables is well known to cure human maladies due to
the presence of bioactive components. Among these compounds, thymoquinone, a …

The multifaceted NF-kB: are there still prospects of its inhibition for clinical intervention in pediatric central nervous system tumors?

M Medeiros, MF Candido, ET Valera… - Cellular and Molecular …, 2021 - Springer
Despite advances in the understanding of the molecular mechanisms underlying the basic
biology and pathogenesis of pediatric central nervous system (CNS) malignancies, patients …

Effect of thymoquinone on the resistance of Cronobacter sakazakii to environmental stresses and antibiotics

Y Chen, Q Wen, S Chen, DU Guo, Y Xu, S Liang, X Xia… - Food Control, 2020 - Elsevier
Cronobacter sakazakii is a foodborne bacterial pathogen with resistance to a wide range of
stress conditions. Here, we investigated the effects of thymoquinone (TQ) on the …

A multiple endpoint approach reveals potential in vitro anticancer properties of thymoquinone in human renal carcinoma cells

JG Costa, V Keser, C Jackson, N Saraiva… - Food and Chemical …, 2020 - Elsevier
Thymoquinone (TQ) is a monoterpene isolated from the oil of Nigella sativa seeds. The aim
of this work was to evaluate the cytotoxic effects induced by TQ and its impact on the …