Structural characterization of MG and pre-MG states of proteins by MD simulations, NMR, and other techniques

A Naiyer, MI Hassan, A Islam, M Sundd… - Journal of Biomolecular …, 2015 - Taylor & Francis
Almost all proteins fold via a number of partially structured intermediates such as molten
globule (MG) and pre-molten globule states. Understanding the structure of these …

Role of N-terminal residues on folding and stability of C-phycoerythrin: simulation and urea-induced denaturation studies

K Anwer, R Sonani, D Madamwar, P Singh… - Journal of …, 2015 - Taylor & Francis
The conformational state of biliproteins can be determined by optical properties of the
covalently linked chromophores. Recently determined crystal structure of truncated form of α …

The concept of protein folding/unfolding and its impacts on human health

L Alaei, M Ashengroph… - Advances in protein …, 2021 - Elsevier
Proteins have evolved in specific 3D structures and play different functions in cells and
determine various reactions and pathways. The newly synthesized amino acid chains once …

Combinatorial High-Throughput Screening of Complex Polymeric Enzyme Immobilization Supports

H Sánchez-Morán, JL Kaar… - Journal of the American …, 2024 - ACS Publications
Recent advances have demonstrated the promise of complex multicomponent polymeric
supports to enable supra-biological enzyme performance. However, the discovery of such …

[HTML][HTML] Synthesis of dietetic structured lipids from spent coffee grounds crude oil catalyzed by commercial immobilized lipases and immobilized Rhizopus oryzae …

DA Mota, JCB Santos, D Faria, ÁS Lima, LC Krause… - Processes, 2020 - mdpi.com
The aim of this study was the valorization of coffee industry residues, namely spent coffee
grounds (SCG) as a source of oil, and silverskin (CS) as a source of both oil and biomass …

Mechanistic insights into the urea-induced denaturation of kinase domain of human integrin linked kinase

SB Syed, FI Khan, SH Khan, S Srivastava… - International journal of …, 2018 - Elsevier
Abstract Integrin-linked kinase (ILK), a ubiquitously expressed intracellular Ser/Thr protein
kinase, plays a major role in the oncogenesis and tumour progression. The conformational …

Molecular basis of the structural stability of hemochromatosis factor E: A combined molecular dynamic simulation and GdmCl‐induced denaturation study

P Khan, A Parkash, A Islam, F Ahmad… - Biopolymers, 2016 - Wiley Online Library
Hemochromatosis factor E (HFE) is a member of class I MHC family and plays a significant
role in the iron homeostasis. Denaturation of HFE induced by guanidinium chloride (GdmCl) …

Urea-induced denaturation of human calcium/calmodulin-dependent protein kinase IV: a combined spectroscopic and MD simulation studies

H Naz, M Shahbaaz, MA Haque, K Bisetty… - Journal of …, 2017 - Taylor & Francis
Calcium/calmodulin-dependent protein kinase IV (CaMKIV) is a multifunctional enzyme
which belongs to the Ser/Thr kinase family. CaMKIV plays important role in varieties of …

Spectroscopic and MD simulation studies on unfolding processes of mitochondrial carbonic anhydrase VA induced by urea

D Idrees, A Prakash, MA Haque, A Islam… - Journal of …, 2016 - Taylor & Francis
Carbonic anhydrase VA (CAVA) is primarily expressed in the mitochondria and involved in
numerous physiological processes including lipogenesis, insulin secretion from pancreatic …

GdmCl-induced unfolding studies of human carbonic anhydrase IX: a combined spectroscopic and MD simulation approach

A Prakash, D Idrees, MA Haque, A Islam… - Journal of …, 2017 - Taylor & Francis
Carbonic anhydrase IX (CAIX) is a transmembrane glycoprotein, associated with tumor,
acidification which leads to the cancer, and is considered as a potential biomarker for …