The effect of caffeic acid phenethyl ester (CAPE) on metabolic enzymes including acetylcholinesterase, butyrylcholinesterase, glutathione S-transferase …

İ Gülçin, A Scozzafava, CT Supuran… - Journal of enzyme …, 2016 - Taylor & Francis
Caffeic acid phenethyl ester (CAPE) is an active component of honeybee propolis extracts.
Carbonic anhydrases (CAs, EC 4.2. 1.1) are widespread and intensively studied …

Discovery of potent carbonic anhydrase and acetylcholine esterase inhibitors: Novel sulfamoylcarbamates and sulfamides derived from acetophenones

A Akıncıoğlu, H Akıncıoğlu, İ Gülçin, S Durdagi… - Bioorganic & medicinal …, 2015 - Elsevier
In this study, several novel sulfamides were synthesized and evaluated for their
acetylcholine esterase (AChE) and human carbonic anhydrase I, and II isoenzymes (hCA I …

Carbonic anhydrase and acetylcholinesterase inhibitory effects of carbamates and sulfamoylcarbamates

H Göçer, A Akincioğlu, S Göksu, İ Gülçin… - Journal of enzyme …, 2015 - Taylor & Francis
Carbonic anhydrases (CA), as a family of metalloenzymes, are found in almost every type of
tissue and play an important role in catalyzing the equilibration of carbon dioxide and …

Novel sulfamides as potential carbonic anhydrase isoenzymes inhibitors

A Akıncıoğlu, Y Akbaba, H Göçer, S Göksu… - Bioorganic & Medicinal …, 2013 - Elsevier
Sulfamides represent an important class of biologically active compounds. A series of novel
sulfamides were synthesized from 1-aminoindanes, 1-aminotetralin, 2-aminoindanes and 2 …

The synthesis of some β-lactams and investigation of their metal-chelating activity, carbonic anhydrase and acetylcholinesterase inhibition profiles

B Turan, K Şendil, E Şengül, MS Gültekin… - Journal of enzyme …, 2016 - Taylor & Francis
Abstract β-Lactam antibiotics are a broad class of antibiotics, consisting of all antibiotic
agents that contain a β-lactam ring in their molecular structures. Synthesis of β-lactam …

Deltamethrin attenuates antioxidant defense system and induces the expression of heat shock protein 70 in rainbow trout

SB Ceyhun, M Şentürk, D Ekinci, O Erdoğan… - … and Physiology Part C …, 2010 - Elsevier
The current research aims to determine alterations in gene expression and enzymatic
activity of fish antioxidant metabolism in response to pesticide administration. To this end …

Purification and Characterization of Polyphenol Oxidase from Hemşin Apple (Malus communis L.)

B Aydin, I Gulcin, SH Alwasel - International journal of food …, 2015 - Taylor & Francis
The polyphenol oxidase (PPO) enzyme was purified and characterized from Hemşin Apple
(Malus communis L.), which was organically grown in Hemşin, in the Rize province of …

Synthesis and carbonic anhydrase inhibitory properties of sulfamides structurally related to dopamine

K Aksu, M Nar, M Tanc, D Vullo, İ Gülçin… - Bioorganic & medicinal …, 2013 - Elsevier
A series of novel sulfamides incorporating the dopamine scaffold were synthesized.
Reaction of amines and tert-butyl-alcohol/benzyl alcohol in the presence of chlorosulfonyl …

Synthesis and bioactivity of several new hetaryl sulfonamides

P Taslimi, A Sujayev, S Mamedova, P Kalın… - Journal of enzyme …, 2017 - Taylor & Francis
(4-Methylsulfonyl)-2-thione-4-aryl-5-Z-6-methyl and oxyalkyl-imidazoles were synthesized
from different tetrahydropyrimidinethiones and aryl sulfonyl chloride. These compunds were …

The effects of some cephalosporins on acetylcholinesterase and glutathione S-transferase: an in vivo and in vitro study

F Türkan, Z Huyut, Y Demir, F Ertaş… - Archives of physiology …, 2019 - Taylor & Francis
Abstract Background: Glutathione S-transferase (GST) and acetylcholinesterase (AChE) are
important enzymes in the metabolism. GSTs are primarily available in phase II metabolism …