Antitrypanosomal activity of Verbascum sinaiticum Benth. (Scrophulariaceae) against Trypanosoma congolense isolates

E Mergia, W Shibeshi, G Terefe… - BMC complementary and …, 2016 - Springer
Abstract Background African Trypanosomiasis is a neglected tropical disease with a large
impact on the livelihood of the rural poor in Sub-Saharan Africa. The available drugs for …

Toxicity study and anti-trypanosomal activities of aqueous and methanol whole plant extracts of Brillantaisia owariensis on Trypanosoma brucei-induced infection in …

NG Ayawa, SB Ramon-Yusuf, YA Wada, SJ Oniye… - Clinical …, 2021 - Springer
Background The problem of drug resistance and toxicity in trypanosomiasis is ever-
increasing, thereby creating a need to search for efficacious and safer alternatives that are of …

Isolation and Antitrypanosomal Characterization of Furoquinoline and Oxylipin from Zanthoxylum zanthoxyloides

AK Dofuor, F Ayertey, P Bolah, GI Djameh, K Kyeremeh… - Biomolecules, 2020 - mdpi.com
In the absence of vaccines, there is a need for alternative sources of effective chemotherapy
for African trypanosomiasis (AT). The increasing rate of resistance and toxicity of …

[PDF][PDF] Phytochemical screening and in vitro antitrypanosomal activity of aqueous and methanol leaf extract of verbascum sinaiticum (scrophulariaceae) against …

E Mergia, W Shibeshi, G Terefe, T Teklehaymanot - Lab. Anim, 2014 - scholar.archive.org
Aqueous and methanol leaf extracts of V. sinaiticum were investigated for the presence of
secondary metabolites and their in vitro activity against Trypanosoma congolence, the main …

Potential anti-trypanosomal plants against African animal trypanosmiasis

S Assefa - Journal of Pharmacognosy and Phytochemistry, 2017 - phytojournal.com
The genus Trypanosoma, which is a flagellated protozoan, causes trypanosomiasis. The
disease can be occurred in human and animals in Africa and South America. African animal …

[PDF][PDF] Phytochemical screening and

E Mergia, G Terefe, T Teklehaymanot, W Shibeshi - 2014 - academia.edu
Aqueous and methanol leaf extracts of V. sinaiticum were investigated for the presence of
secondary metabolites and their in vitro activity against Trypanosoma congolence, the main …

[PDF][PDF] Phytochemical screening and in vitro antitrypanosomal activity of aqueous and methanol leaf extract of Clutia abyssinica (Euphorbiaceae) against …

E Mergia, G Terefe, T Teklehaymanot… - Pharmacologia, 2015 - researchgate.net
Background and Objectives: There is urgent need of search for alternative compounds for
chemotherapy of African trypanosomiasis, a disease of major economic and public health …

[PDF][PDF] Evaluation of

E Mergia, W Shibeshi, G Terefe, T Teklehaymanot - 2014 - academia.edu
Natural Products Chemistry & Research Page 1 Volume 2 • Issue 4 • 1000138 Nat Prod Chem
Res ISSN: 2329-6836 NPCR, an open access journal Mergia et al., Nat Prod Chem Res 2014 …

Evaluation of the in-vivo antitrypanosomal activity of the crude extract of Moringa oleifera (lam) against rats infected with Trypanosoma brucei

D Yau, M Ibrahim, AU Lado… - GSC Biological and …, 2020 - gsconlinepress.com
The anti-typanosomal effect of the crude extract of the leaves of Moringa oleifera was
determined in-vivo in Trypanosoma brucei-infected rats. In the study, twenty five rats …

Subfamily Bombacoideae: Traditional Uses, Secondary Metabolites, Biological Activities, and Mechanistic Interpretation of the Anti-Inflammatory Activity of its Species

MIG El-Din, FS Youssef, ML Ashour, OA Eldahshan… - Wild …, 2020 - taylorfrancis.com
Phytochemical investigations of Bombacoideae resulted in the identification of almost 160
secondary metabolites belonging to various chemical classes, including flavonoids, lignans …