Stem cells are a population of undifferentiated cells characterized by the ability to
extensively proliferate (self-renewal), usually arise from a single cell (clonal), and …

Stem cells including embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs)
and adult stem cells (ASCs) are able to repair/replace damaged or degenerative tissues and …

Idiopathic pulmonary fibrosis (IPF) is characterized by chronic inflammation, severe scarring,
and stem cell senescence. Stem cell-based therapies modulate inflammatory and fibrogenic …

Pulmonary alveolar proteinosis (PAP) is a diffuse lung disease that results from the
accumulation of lipoproteinaceous material in the alveoli and alveolar macrophages due to …

EXECUTIVE SUMMARY The University of Vermont College of Medicine and the Vermont
Lung Center, with support of the National Heart, Lung, and Blood Institute (NHLBI), the …

Extracellular vesicles (EVs), a cluster of cell-secreted lipid bilayer nanoscale particles,
universally exist in body fluids, as well as cell and tissue culture supernatants. Over the past …

Premature newborns are at a higher risk for the development of respiratory distress
syndrome (RDS), acute lung injury (ALI) associated with lung inflammation, disruption of …

Perinatal hypoxic–ischemic brain injury remains a major cause of cerebral palsy. Although
therapeutic hypothermia is now established to improve recovery from hypoxia–ischemia (HI) …

Among the many cell types useful in developing therapeutic treatments, human amniotic
cells from placenta have been proposed as valid candidates. Both human amniotic epithelial …

Epithelial and mesenchymal cells isolated from the amniotic membrane (AM) possess stem
cell characteristics, differentiation potential toward lineages of different germ layers, and …