Otitis media (OM) is an infective and inflammatory disorder known to be a major cause of
hearing impairment across all age groups. Both acute and chronic OM result in substantial …

The pathogenesis of otitis media (OM), an inflammatory disease of the middle ear (ME),
involves interplay between many different factors, including the pathogenicity of infectious …

Auditory bulla cavitation defects are a cause of otitis media, but the normal cellular pattern of
bulla mesenchyme regression and its failure are not well understood. In mice, neural-crest …

Recurrent and chronic otitis media (OM) are often refractory to antibiotics due to bacterial
persistence in biofilm within the middle ear. In vitro and in vivo studies have demonstrated …

Objective To review the most recent advances in human and bacterial genomics as applied
to pathogenesis and clinical management of otitis media. Data sources PubMed articles …

Otitis media (OM) is the most common paediatric disease and leads to significant morbidity.
Although understanding of underlying disease mechanisms is hampered by complex …

Short palate, lung, and nasal epithelium clone 1 (SPLUNC1) is a kind of secretory protein,
and gets expressed abundantly in normal respiratory epithelium of humans. As a natural …

Objective To summarize recently published key articles on the topics of biomedical
engineering, biotechnology and new models in relation to otitis media (OM). Data sources …

Bactericidal/permeability-increasing protein fold-containing family member A1 (BPIFA1) is
abundantly secreted protein of the upper airways that plays a pleiotropic role in airway …

Background: Chronic inflammation of the middle ear, known as chronic otitis media, is a
debilitating condition of unknown aetiology that causes hearing loss in children and adults …