Perspective: Vitamin D deficiency and COVID‐19 severity–plausibly linked by latitude, ethnicity, impacts on cytokines, ACE2 and thrombosis

JM Rhodes, S Subramanian, E Laird… - Journal of internal …, 2021 - Wiley Online Library
Background SARS‐CoV‐2 coronavirus infection ranges from asymptomatic through to fatal
COVID‐19 characterized by a 'cytokine storm'and lung failure. Vitamin D deficiency has …

[HTML][HTML] The importance of vitamin d metabolism as a potential prophylactic, immunoregulatory and neuroprotective treatment for COVID-19

Y Xu, DJ Baylink, CS Chen, ME Reeves, J Xiao… - Journal of translational …, 2020 - Springer
Abstract The coronavirus disease 2019 (COVID-19) pandemic has led to a declaration of a
Public Health Emergency of International Concern by the World Health Organization. As of …

Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data

AR Martineau, DA Jolliffe, RL Hooper, L Greenberg… - bmj, 2017 - bmj.com
Objectives To assess the overall effect of vitamin D supplementation on risk of acute
respiratory tract infection, and to identify factors modifying this effect. Design Systematic …

[HTML][HTML] Gut microbiota-derived metabolites in irritable bowel syndrome

L Xiao, Q Liu, M Luo, L Xiong - Frontiers in Cellular and Infection …, 2021 - frontiersin.org
Irritable bowel syndrome (IBS) is the most common functional bowel disorder worldwide and
is associated with visceral hypersensitivity, gut motility, immunomodulation, gut microbiota …

Effect of vitamin D supplementation on non-skeletal disorders: a systematic review of meta-analyses and randomised trials

P Autier, P Mullie, A Macacu, M Dragomir… - The lancet Diabetes & …, 2017 - thelancet.com
Randomised trials reported up to Dec 31, 2012, did not confirm that vitamin D
supplementation could protect from non-skeletal health conditions affecting adults, as was …

[HTML][HTML] Vitamin D, autoimmune disease and rheumatoid arthritis

SR Harrison, D Li, LE Jeffery, K Raza… - Calcified tissue …, 2020 - Springer
Vitamin D has been reported to influence physiological systems that extend far beyond its
established functions in calcium and bone homeostasis. Prominent amongst these are the …

Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis

AR Martineau, DA Jolliffe, L Greenberg, JF Aloia… - 2019 - figshare.utas.edu.au
Background: Randomised controlled trials (RCTs) exploring the potential of vitamin D to
prevent acute respiratory infections have yielded mixed results. Individual participant data …

[HTML][HTML] The impact of vitamin D levels on inflammatory status: a systematic review of immune cell studies

EK Calton, KN Keane, P Newsholme, MJ Soares - PloS one, 2015 - journals.plos.org
Chronic low-grade inflammation accompanies obesity and its related chronic conditions.
Both peripheral blood mononuclear cells (PBMCs) and cell lines have been used to study …

The serum vitamin D metabolome: What we know and what is still to discover

RC Tuckey, CYS Cheng, AT Slominski - The Journal of steroid biochemistry …, 2019 - Elsevier
Vitamin D, referring to the two forms, D2 from the diet and D3 primarily derived from
phototransformation in the skin, is a prohormone important in human health. The most …

[HTML][HTML] Immunomodulatory effects of vitamin D in pregnancy and beyond

F Cyprian, E Lefkou, K Varoudi, G Girardi - Frontiers in immunology, 2019 - frontiersin.org
In addition to its role in calcium homeostasis and bone formation, a modulatory role of the
active form of vitamin D on cells of the immune system, particularly T lymphocytes, has been …