[HTML][HTML] Current advances in ischemic stroke research and therapies

D Barthels, H Das - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2020 - Elsevier
With more than 795,000 cases occurring every year, stroke has become a major problem in
the United States across all demographics. Stroke is the leading cause of long-term …

The potential impact of neuroimaging and translational research on the clinical management of lacunar stroke

S Rudilosso, A Rodríguez-Vázquez, X Urra… - International journal of …, 2022 - mdpi.com
Lacunar infarcts represent one of the most frequent subtypes of ischemic strokes and may
represent the first recognizable manifestation of a progressive disease of the small …

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

R Malik, G Chauhan, M Traylor, M Sargurupremraj… - Nature …, 2018 - nature.com
Stroke has multiple etiologies, but the underlying genes and pathways are largely unknown.
We conducted a multiancestry genome-wide-association meta-analysis in 521,612 …

Multilevel omics for the discovery of biomarkers and therapeutic targets for stroke

J Montaner, L Ramiro, A Simats, S Tiedt… - Nature Reviews …, 2020 - nature.com
Despite many years of research, no biomarkers for stroke are available to use in clinical
practice. Progress in high-throughput technologies has provided new opportunities to …

Embolic strokes of undetermined source: the case for a new clinical construct

RG Hart, HC Diener, SB Coutts, JD Easton… - The Lancet …, 2014 - thelancet.com
Cryptogenic (of unknown cause) ischaemic strokes are now thought to comprise about 25%
of all ischaemic strokes. Advances in imaging techniques and improved understanding of …

Diagnosis and management of acute ischemic stroke: speed is critical

TD Musuka, SB Wilton, M Traboulsi, MD Hill - Cmaj, 2015 - Can Med Assoc
Stroke syndromes present clinically as neurologic deficits of sudden onset. Symptoms
depend upon the affected region of brain, which in turn is defined by the arterial anatomy …

Review and update of the concept of embolic stroke of undetermined source

HC Diener, JD Easton, RG Hart, S Kasner… - Nature Reviews …, 2022 - nature.com
Ischaemic strokes have traditionally been classified according to the TOAST criteria, in
which strokes with unclear aetiology are classified as cryptogenic strokes. However, the …

[HTML][HTML] Acute ischemic stroke: management approach

C Chugh - Indian journal of critical care medicine: peer-reviewed …, 2019 - ncbi.nlm.nih.gov
Acute Ischemic Stroke: Management Approach - PMC Back to Top Skip to main content NIH
NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation …

Proposal for updated nomenclature and classification of potential causative mechanism in patent foramen ovale–associated stroke

AY Elgendy, JL Saver, Z Amin, KD Boudoulas… - JAMA …, 2020 - jamanetwork.com
Importance Recent epidemiologic and therapeutic advances have transformed
understanding of the role of and therapeutic approach to patent foramen ovale (PFO) in …

Ischaemic stroke in young adults: risk factors and long-term consequences

NAMM Maaijwee, LCA Rutten-Jacobs… - Nature Reviews …, 2014 - nature.com
Contrary to trends in most other diseases, the average age of ischaemic stroke onset is
decreasing, owing to a rise in the incidence of stroke among'young'individuals (under 50 …