Traumatic brain injury (TBI) presents in various forms ranging from mild alterations of
consciousness to an unrelenting comatose state and death. In the most severe form of TBI …

The adult brain is a plastic place. To ensure that the mature nervous system's control of
behaviour is flexible in the face of a varying environment, morphological and physiological …

Aims Neurogenesis in the postnatal human brain occurs in two neurogenic niches; the
subventricular zone (SVZ) in the wall of the lateral ventricles and the subgranular zone …

Transformed stem cells have been isolated from some human cancers. We report that,
unlike other brain cancers, the lethal glioblastoma multiforme contains neural precursors …

Seven secretory mammalian kexin-like subtilases have been identified that cleave a variety
of precursor proteins at monobasic and dibasic residues. The recently characterized …

Continuous turnover of neurons in the olfactory bulb is implicated in several key aspects of
olfaction. There is a dramatic decline postnatally in the number of migratory neuroblasts en …

The subventricular zone (SVZ) is a principal source of adult neural stem cells in the rodent
brain, generating thousands of olfactory bulb neurons every day. If the adult human brain …

The dogma that the genesis of new cells is a negligible event in the adult mammalian brain
has long influenced our perception and understanding of the origin and development of …

Stroke causes cell death but also birth and migration of new neurons within sites of ischemic
damage. The cellular environment that induces neuronal regeneration and migration after …

Neural stem cells (NSCs) have a unique role in neural regeneration. Cell therapy based on
NSC transplantation is a promising tool for the treatment of nervous system diseases …