Tumor-Specific Positron Emission Tomography Imaging in Patients: [18F] Fluorodeoxyglucose and Beyond

DA Mankoff, JF Eary, JM Link, M Muzi… - Clinical cancer …, 2007 - AACR
Biochemical and molecular imaging of cancer using positron emission tomography (PET)
plays an increasing role in the care of cancer patients. Most clinical work to date uses the …

Evolving role of positron emission tomography in breast cancer imaging

WB Eubank, DA Mankoff - Seminars in nuclear medicine, 2005 - Elsevier
18F-fluorodeoxyglucose positron emission tomography (FDG-PET) has been used for
detection, staging, and response monitoring in breast cancer patients. Although studies …

Microcirculation and microvasculature in breast tumors: pharmacokinetic analysis of dynamic MR image series

G Brix, F Kiessling, R Lucht, S Darai… - … in Medicine: An …, 2004 - Wiley Online Library
The purpose of this study was to quantify microcirculation and microvasculature in breast
lesions by pharmacokinetic analysis of Gd‐DTPA‐enhanced MRI series. Strongly T1 …

Evaluation of a cumulative SUV-volume histogram method for parameterizing heterogeneous intratumoural FDG uptake in non-small cell lung cancer PET studies

FHP van Velden, P Cheebsumon, M Yaqub… - European journal of …, 2011 - Springer
Purpose Standardized uptake values (SUV) are commonly used for quantification of whole-
body [18 F] fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET) studies …

High‐resolution fluorodeoxyglucose positron emission tomography with compression (“positron emission mammography”) is highly accurate in depicting primary …

WA Berg, IN Weinberg, D Narayanan… - The breast …, 2006 - Wiley Online Library
We sought to prospectively assess the diagnostic performance of a high‐resolution positron
emission tomography (PET) scanner using mild breast compression (positron emission …

Decreased blood flow with increased metabolic activity: a novel sign of pancreatic tumor aggressiveness

G Komar, S Kauhanen, K Liukko, M Seppänen… - Clinical Cancer …, 2009 - AACR
Purpose: To study blood flow (BF) and metabolism in normal pancreas and in different
pancreatic lesions. We then determined the effect of these biomarkers on outcome in …

Dependence of FDG uptake on tumor microenvironment

A Pugachev, S Ruan, S Carlin, SM Larson… - International Journal of …, 2005 - Elsevier
Purpose: To investigate the factors affecting the 18F-fluorodeoxyglucose (18F-FDG) uptake
in tumors at a microscopic level, by correlating it with tumor hypoxia, cellular proliferation …

Tumor metabolism and blood flow changes by positron emission tomography: relation to survival in patients treated with neoadjuvant chemotherapy for locally …

LK Dunnwald, JR Gralow, GK Ellis… - Journal of Clinical …, 2008 - ascopubs.org
Purpose Patients with locally advanced breast carcinoma (LABC) receive preoperative
chemotherapy to provide early systemic treatment and assess in vivo tumor response. Serial …

18F-FDG PET/CT for image-guided and intensity-modulated radiotherapy

EC Ford, J Herman, E Yorke… - Journal of Nuclear …, 2009 - Soc Nuclear Med
Advances in technology have allowed extremely precise control of radiation dose delivery
and localization within a patient. The ability to confidently delineate target tumor boundaries …

18F-FDG kinetics in locally advanced breast cancer: correlation with tumor blood flow and changes in response to neoadjuvant chemotherapy

J Tseng, LK Dunnwald, EK Schubert… - Journal of Nuclear …, 2004 - Soc Nuclear Med
The aim of this study was to characterize the biologic response of locally advanced breast
cancer (LABC) to chemotherapy using 15O-water–derived blood flow measurements and …