[HTML][HTML] Identifying genetic variants underlying medication-induced osteonecrosis of the jaw in cancer and osteoporosis: a case control study
KH Lee, SH Kim, CH Kim, BJ Min, GJ Kim, Y Lim… - Journal of Translational …, 2019 - Springer
Background Bisphosphonate-induced osteonecrosis of the jaw (BRONJ) presents with a
typical pattern of jaw necrosis in patients who have been prescribed bisphosphonates (BPs) …
typical pattern of jaw necrosis in patients who have been prescribed bisphosphonates (BPs) …
[HTML][HTML] Star allele-based haplotyping versus gene-wise variant burden scoring for predicting 6-mercaptopurine intolerance in pediatric acute lymphoblastic leukemia …
Y Park, H Kim, JY Choi, S Yun, BJ Min… - Frontiers in …, 2019 - frontiersin.org
Nudix Hydrolase 15 (NUDT15) and Thiopurine S-Methyltransferase (TPMT) are strong
genetic determinants of thiopurine toxicity in pediatric acute lymphoblastic leukemia (ALL) …
genetic determinants of thiopurine toxicity in pediatric acute lymphoblastic leukemia (ALL) …
[HTML][HTML] Genetic markers for later remission in response to early improvement of antidepressants
HJ Kang, KT Kim, KH Yoo, Y Park, JW Kim… - International Journal of …, 2020 - mdpi.com
Planning subsequent treatment strategies based on early responses rather than waiting for
delayed antidepressant action can be helpful. We identified genetic markers for later non …
delayed antidepressant action can be helpful. We identified genetic markers for later non …
New therapeutic target NCF1-directed multi-bioactive conjugate therapies prevent preterm birth and adverse pregnancy outcomes
J Cheng, X Jia, L Yang, S Zhang, Z Chen, Q Gui, T Li… - Science Bulletin, 2024 - Elsevier
Preterm birth (PTB) is a leading cause of neonatal morbidity and mortality worldwide, yet the
cellular and molecular mechanisms driving this condition remain undeciphered, thus limiting …
cellular and molecular mechanisms driving this condition remain undeciphered, thus limiting …
Unveiling the genetic variation of severe continuous/mixed-type ossification of the posterior longitudinal ligament by whole-exome sequencing and bioinformatic …
ABSTRACT BACKGROUND CONTEXT Ossification of the posterior longitudinal ligament
(OPLL) in the cervical spine is known as a rare, complex genetic disease, its complexity …
(OPLL) in the cervical spine is known as a rare, complex genetic disease, its complexity …
Tocolytic treatment and maternal characteristics, obstetric outcomes, and offspring childhood outcomes among births at and after 37 weeks of gestation: the Japan …
T Murata, H Isogami, K Imaizumi, T Fukuda… - Archives of Gynecology …, 2024 - Springer
Purpose To evaluate differences in maternal characteristics and obstetric and offspring
childhood outcomes between births at and after 37 weeks of gestation (referred to as term …
childhood outcomes between births at and after 37 weeks of gestation (referred to as term …
[HTML][HTML] Personal genome testing on physicians improves attitudes on pharmacogenomic approaches
KH Lee, BJ Min, JH Kim - PloS one, 2019 - journals.plos.org
In this era of clinical genomics, the accumulation of knowledge of pharmacogenomics (PGx)
is rising dramatically and attempts to utilize it in clinical practice are also increasing …
is rising dramatically and attempts to utilize it in clinical practice are also increasing …
[HTML][HTML] Genetic susceptibility to post-endoscopic retrograde cholangiopancreatography pancreatitis identified in propensity score-matched analysis
YH Choi, Y Lim, DK Jang, DW Ahn, JK Ryu… - The Korean Journal …, 2023 - ncbi.nlm.nih.gov
Methods A cohort of high-risk PEP patients was queried from December 2016 to January
2019. For each PEP case, two propensity score-matched controls were selected. Whole …
2019. For each PEP case, two propensity score-matched controls were selected. Whole …
[HTML][HTML] Identifying genetic variants associated with ritodrine-induced pulmonary edema
SM Lee, Y Park, YJ Kim, HS Hwang, H Seo, BJ Min… - PloS one, 2020 - journals.plos.org
Introduction Ritodrine is one of the most commonly used tocolytics in preterm labor, acting
as a ß2-adrenergic agonist that reduces intracellular calcium levels and prevents myometrial …
as a ß2-adrenergic agonist that reduces intracellular calcium levels and prevents myometrial …
[HTML][HTML] Gene-wise burden of coding variants correlates to noncoding pharmacogenetic risk variants
J Park, SY Lee, SY Baik, CH Park, JH Yoon… - International Journal of …, 2020 - mdpi.com
Genetic variability can modulate individual drug responses. A significant portion of
pharmacogenetic variants reside in the noncoding genome yet it is unclear if the noncoding …
pharmacogenetic variants reside in the noncoding genome yet it is unclear if the noncoding …