Adjuvant physiochemistry and advanced nanotechnology for vaccine development

H Ren, W Jia, Y Xie, M Yu, Y Chen - Chemical Society Reviews, 2023 - pubs.rsc.org
Vaccines comprising innovative adjuvants are rapidly reaching advanced translational
stages, such as the authorized nanotechnology adjuvants in mRNA vaccines against COVID …

Therapeutic supramolecular polymers: Designs and applications

H Wang, J Mills, B Sun, H Cui - Progress in Polymer Science, 2023 - Elsevier
The self-assembly of low-molecular-weight building motifs into supramolecular polymers
has unlocked a new realm of materials with distinct properties and tremendous potential for …

Peptide‐based supramolecular therapeutics for fighting major diseases

Z Wang, H Luo, H Wang, M Xiao, H Jia… - Advanced Functional …, 2024 - Wiley Online Library
Peptide‐based supramolecular therapeutics (PST) refer to those theranostic nanomedicines
based on peptide or peptide derivatives self‐assembly that are constructed in vitro or in vivo …

Next-Generation Vaccine Development with Nanomaterials: Recent Advances, Possibilities, and Challenges

S Shetty, PC Alvarado, D Pettie… - Annual Review of …, 2024 - annualreviews.org
Nanomaterials are becoming important tools for vaccine development owing to their tunable
and adaptable nature. Unique properties of nanomaterials afford opportunities to modulate …

Chemical and biological conjugation strategies for the development of multivalent protein vaccine nanoparticles

J Park, T Pho, JA Champion - Biopolymers, 2023 - Wiley Online Library
The development of subunit vaccine platforms has been of considerable interest due to their
good safety profile and ability to be adapted to new antigens, compared to other vaccine …

Polyfunctional antibodies: a path towards precision vaccines for vulnerable populations

RA Purcell, RM Theisen, KB Arnold… - Frontiers in …, 2023 - frontiersin.org
Vaccine efficacy determined within the controlled environment of a clinical trial is usually
substantially greater than real-world vaccine effectiveness. Typically, this results from …

From antigen uptake to immune modulation: the multifaceted potential of peptide nanofibers as vaccine nanocarriers

HAFM Hassan, M Haider, SA Fahmy - Materials Advances, 2024 - pubs.rsc.org
Spanning from the mitigation of pathogenic diseases via protective immunity to the provision
of therapeutic solutions for other debilitating ailments, immune-based interventions have …

Development and evaluation of self-assembling nanovaccine for immune protection against spring viremia of carp

TZ Sun, PQ Zhang, C Zhang, HF Jiang, B Zhu - Aquaculture, 2024 - Elsevier
Self-assembled peptides have become a hot topic in research on new fishery-immersed
nanovaccines due to their physical and chemical properties and efficient carrying capacity …

A stabilized MERS-CoV spike ferritin nanoparticle vaccine elicits robust and protective neutralizing antibody responses

AE Powell, H Caruso, S Park, JL Chen, J O'Rear… - bioRxiv, 2024 - biorxiv.org
Middle East respiratory syndrome coronavirus (MERS-CoV) was first identified as a human
pathogenic virus in 2012 and is causing ongoing sporadic infections as well as outbreak …