Alkaline phosphatase (ALP), which catalyzes the dephosphorylation process of proteins,
nucleic acids, and small molecules, can be found in a variety of tissues (intestine, liver …

Parenteral nutrition (PN) is a common therapy for preterm, very low birthweight (VLBW;
birthweight< 1500 g), and other high-risk newborns. PN is required for the period when …

Tumorigenic risk of undifferentiated human induced pluripotent stem cells (iPSCs), being a
major obstacle for clinical application of iPSCs, requires novel approaches for selectively …

Despite the importance of early recognition of metabolic bone disease (MBD) of prematurity,
there is still significant variability in screening practices across institutions. We conducted an …

We developed a triple-readout probe for colorimetric, fluorescent, and fluorescence-lifetime
sensing of alkaline phosphatase (ALP) through the hydrolyzed ascorbic acid phosphate …

Mineral accretion by the skeleton before birth depends directly on the adequacy of mineral
supply in utero. This mineral supply also regulates the functional activity of the osteoblasts …

Background: With current Ca and P recommendations for enteral nutrition, preterm infants,
especially VLBW, fail to achieve a bone mineral content (BMC) equivalent to term infants …

Metabolic bone disease (MBD) of prematurity remains a significant comorbid condition in
preterm, low birth weight infants. As the majority of in utero calcium (Ca) and phosphorus …

With the rapid development of physiopathology and the surge in demand for comprehension
of micro-scale physiological events, AIE-based bio-probes are found superior in presenting …

早产儿代谢性骨病（ metabolic bone disease of prematurity， MBDP） 是由于机体钙磷代谢紊乱
导致骨矿物质含量减少的全身性骨骼疾病。 我国目前对MBDP 尚缺乏深入研究和系统认识 …