Mitochondria play key roles in ATP supply, calcium homeostasis, redox balance control and
apoptosis, which in neurons are fundamental for neurotransmission and to allow synaptic …

Alzheimer's disease (AD) is a progressive neurodegenerative disease, and it is currently the
seventh leading cause of death worldwide. It is characterized by the extracellular …

Alzheimer's disease and Type 2 diabetes are pathological processes associated to ageing.
Moreover, there are evidences supporting a mechanistic link between Alzheimer's disease …

Natural autoantibodies, immunoglobulins (Igs) that target self-proteins, are common in the
plasma of healthy individuals; some of the autoantibodies play pathogenic roles in systemic …

Alzheimer's disease (AD) is a neurodegenerative process characterized by the
accumulation of extracellular deposits of amyloid β-peptide (Aβ), which induces neuronal …

Alzheimer's disease (AD) is tightly linked to oxidative stress since amyloid beta‐peptide (Aβ)
aggregates generate free radicals. Moreover, the aggregation of Aβ is increased by …

Alzheimer's disease (AD) is a progressive neurodegenerative condition and the primary
form of dementia among elderly people. The amyloidogenic hypothesis is the main theory …

The accumulation of amyloid-β (Aβ) aggregates, a distinct pathological feature in
Alzheimer's disease (AD), prompts exploration into mechanisms for Aβ clearance from …

Amyloid β-peptide (Aβ) misfolding into β-sheet structures triggers neurotoxicity inducing
Alzheimer's disease (AD). Molecules able to reduce or to impair Aβ aggregation are highly …

Tachykinins are short neuropeptides, such as substance P and neurokinin B, that have been
shown to interact with Alzheimer's β-amyloid (Aβ) peptide. Neurokinin A (NKA) is a secreted …