Epigenetics and cervical cancer: from pathogenesis to therapy
J Fang, H Zhang, S Jin - Tumor Biology, 2014 - Springer
Although human papillomavirus (HPV) infection has been found in most of the cervical
cancer cases, additional genetic and epigenetic changes are required for disease …
cancer cases, additional genetic and epigenetic changes are required for disease …
Utility of methylation markers in cervical cancer early detection: appraisal of the state-of-the-science
N Wentzensen, ME Sherman, M Schiffman… - Gynecologic …, 2009 - Elsevier
OBJECTIVE: We wanted to identify the most promising methylation marker candidates for
cervical cancer early detection. METHODS: A systematic literature review was performed in …
cervical cancer early detection. METHODS: A systematic literature review was performed in …
[HTML][HTML] (-)-Epigallocatechin-3-gallate reverses the expression of various tumor-suppressor genes by inhibiting DNA methyltransferases and histone deacetylases in …
There has been increasing evidence that numerous bioactive dietary agents can hamper the
process of carcinogenesis by targeting epigenetic alterations including DNA methylation …
process of carcinogenesis by targeting epigenetic alterations including DNA methylation …
[HTML][HTML] Detection of host cell gene/HPV DNA methylation markers: a promising triage approach for cervical cancer
L Zhang, W Tan, H Yang, S Zhang, Y Dai - Frontiers in Oncology, 2022 - frontiersin.org
Cervical cancer is the most prevalent gynecologic malignancy, especially in women of low-
and middle-income countries (LMICs). With a better understanding of the etiology and …
and middle-income countries (LMICs). With a better understanding of the etiology and …
[HTML][HTML] Epigenetic alterations in preneoplastic and neoplastic lesions of the cervix
Cervical cancer (CC) is one of the most malignant tumors and the second or third most
common type of cancer in women worldwide. The association between human …
common type of cancer in women worldwide. The association between human …
Epigenetic alterations in cervical carcinogenesis
During cervical carcinogenesis, the major etiologic factor, the persistent oncogenic HPV
infection itself is not sufficient to immortalize and transform the epithelial host cells. Together …
infection itself is not sufficient to immortalize and transform the epithelial host cells. Together …
[HTML][HTML] Aberrant DNA methylation in cervical carcinogenesis
HJ Yang - Chinese journal of cancer, 2013 - ncbi.nlm.nih.gov
Persistent infection with high-risk types of human papillomavirus (HPV) is known to cause
cervical cancer; however, additional genetic and epigenetic alterations are required for …
cervical cancer; however, additional genetic and epigenetic alterations are required for …
[HTML][HTML] Sequential gene promoter methylation during HPV-induced cervical carcinogenesis
FE Henken, SM Wilting, RM Overmeer… - British journal of …, 2007 - nature.com
We aimed to link DNA methylation events occurring in cervical carcinomas to distinct stages
of HPV-induced transformation. Methylation specific-multiplex ligation-dependent probe …
of HPV-induced transformation. Methylation specific-multiplex ligation-dependent probe …
Assessment of gene promoter hypermethylation for detection of cervical neoplasia
GBA Wisman, ER Nijhuis, MO Hoque… - … journal of cancer, 2006 - Wiley Online Library
Current cervical cancer screening is based on morphological assessment of Pap smears
and associated with significant false negative and false positive results. Previously, we have …
and associated with significant false negative and false positive results. Previously, we have …
Association between dense CADM1 promoter methylation and reduced protein expression in high‐grade CIN and cervical SCC
RM Overmeer, FE Henken, PJF Snijders… - The Journal of …, 2008 - Wiley Online Library
We previously showed that silencing of TSLC1, recently renamed CADM1, is functionally
involved in high‐risk HPV‐mediated cervical carcinogenesis. CADM1 silencing often results …
involved in high‐risk HPV‐mediated cervical carcinogenesis. CADM1 silencing often results …