Engineering nanomaterials for glioblastoma nanovaccination

F Hameedat, BB Mendes, J Conniot… - Nature Reviews …, 2024 - nature.com
Glioblastoma is a lethal brain cancer with treatment resistance stemming from its interactions
with the surrounding microenvironment and obstacles such as the blood–brain barrier …

[HTML][HTML] Poly-l-glutamic acid modification modulates the bio-nano interface of a therapeutic anti-IGF-1R antibody in prostate cancer

S Vicente-Ruiz, A Armiñán, K Maso, E Gallon… - Biomaterials, 2023 - Elsevier
Modifying biological agents with polymers such as polyethylene glycol (PEG) has
demonstrated clinical benefits; however, post-market surveillance of PEGylated derivatives …

Peptide-Functionalized Layer-by-Layer Nanoparticles Demonstrate Improved Blood Brain Barrier Permeability for Glioblastoma Treatment

P Ganesh - 2023 - dspace.mit.edu
The greatest obstacle in the treatment of glioblastomas is the blood-brain barrier (BBB), the
endothelial cells that line the vessels of the brain and are stitched together into a barrier by …