Fluorescence lifetime imaging microscopy: fundamentals and advances in instrumentation, analysis, and applications

R Datta, TM Heaster, JT Sharick… - … of biomedical optics, 2020 - spiedigitallibrary.org
Significance: Fluorescence lifetime imaging microscopy (FLIM) is a powerful technique to
distinguish the unique molecular environment of fluorophores. FLIM measures the time a …

Single-photon avalanche diode imagers in biophotonics: review and outlook

C Bruschini, H Homulle, IM Antolovic, S Burri… - Light: Science & …, 2019 - nature.com
Single-photon avalanche diode (SPAD) arrays are solid-state detectors that offer imaging
capabilities at the level of individual photons, with unparalleled photon counting and time …

Single-shot ultrafast imaging attaining 70 trillion frames per second

P Wang, J Liang, LV Wang - Nature communications, 2020 - nature.com
Real-time imaging of countless femtosecond dynamics requires extreme speeds orders of
magnitude beyond the limits of electronic sensors. Existing femtosecond imaging modalities …

Fluorescent labeling and modification of proteins

CP Toseland - Journal of chemical biology, 2013 - Springer
This review provides an outline for fluorescent labeling of proteins. Fluorescent assays are
very diverse providing the most sensitive and robust methods for observing biological …

Fluorescence lifetime imaging (FLIM): Basic concepts and some recent developments

K Suhling, LM Hirvonen, JA Levitt, PH Chung… - Medical photonics, 2015 - Elsevier
Fluorescence lifetime imaging (FLIM) is a key fluorescence microscopy technique to map the
environment and interaction of fluorescent probes. It can report on photophysical events that …

Label‐free molecular imaging of biological cells and tissues by linear and nonlinear Raman spectroscopic approaches

C Krafft, M Schmitt, IW Schie… - Angewandte Chemie …, 2017 - Wiley Online Library
Raman spectroscopy is an emerging technique in bioanalysis and imaging of biomaterials
owing to its unique capability of generating spectroscopic fingerprints. Imaging cells and …

Self-sensing intelligent microrobots for noninvasive and wireless monitoring systems

Z Li, K Wang, C Hou, C Li, F Zhang, W Ren… - Microsystems & …, 2023 - nature.com
Microrobots have garnered tremendous attention due to their small size, flexible movement,
and potential for various in situ treatments. However, functional modification of microrobots …

Compressive hyperspectral time-resolved wide-field fluorescence lifetime imaging

Q Pian, R Yao, N Sinsuebphon, X Intes - Nature photonics, 2017 - nature.com
Spectrally resolved fluorescence lifetime imaging,, and spatial multiplexing,, have offered
information content and collection-efficiency boosts in microscopy, but efficient …

Sapphire shaped crystals for waveguiding, sensing and exposure applications

GM Katyba, KI Zaytsev, IN Dolganova… - Progress in Crystal …, 2018 - Elsevier
Second half of the XX century was marked by a rapid development of sapphire shaped
crystal growth technologies, driven by the demands for fast, low-cost, and technologically …

Long‐Lived Second Near‐Infrared Luminescent Probes: An Emerging Role in Time‐Resolved Luminescence Bioimaging and Biosensing

R Feng, G Li, CN Ko, Z Zhang, JB Wan… - Small …, 2023 - Wiley Online Library
Luminescence bioimaging and biosensing in the second near‐infrared (NIR‐II) spectral
window (1,000–1,700 nm wavelengths) is a newly emerging technique that is extensively …