Effects of ethanol on mechanical allodynia and dynamic weight bearing in male and female mice with spared nerve injury
MA Nothem, JR Wickman… - Alcohol: Clinical and …, 2023 - Wiley Online Library
Background Men and women with chronic pain report increased alcohol use and are more
likely to be diagnosed with alcohol use disorder. The relationship between alcohol use and …
likely to be diagnosed with alcohol use disorder. The relationship between alcohol use and …
Analgesic effect of perineural injection of BoNT/A on neuropathic pain induced by chronic constriction injury of sciatic nerve in rats
J He, X Wei, M Wu, Z Song, L Jiang, W Zhang - Neurochemical Research, 2023 - Springer
This study was designed to investigate the analgesic effect of perineural injection of BoNT/A
on neuropathic pain induced by sciatic nerve chronic constriction injury (CCI) and possible …
on neuropathic pain induced by sciatic nerve chronic constriction injury (CCI) and possible …
Advanced dynamic weight bearing as an observer-independent measure of hyperacute hypersensitivity in mice
JO Dent, JP Segal, A Brécier, HGM Gowdy… - Canadian Journal of …, 2023 - Taylor & Francis
Background Standard methods assessing pain in rodents are often observer dependent,
potentially resulting in biased outcomes. Advanced dynamic weight bearing (ADWB) offers …
potentially resulting in biased outcomes. Advanced dynamic weight bearing (ADWB) offers …
Focused ultrasound-induced inhibition of peripheral nerve fibers in an animal model of acute pain
TA Anderson, C Pacharinsak… - Regional Anesthesia & …, 2023 - rapm.bmj.com
Background Moderate-to-severe acute pain is prevalent in many healthcare settings and
associated with adverse outcomes. Peripheral nerve blockade using traditional needle …
associated with adverse outcomes. Peripheral nerve blockade using traditional needle …
[HTML][HTML] Thermal escape box: A cost-benefit evaluation paradigm for investigating thermosensation and thermal pain
JR Dayton, J Marquez, AK Romo, YJ Chen… - Neurobiology of Pain, 2024 - Elsevier
Thermosensation, the ability to detect and estimate temperature, is an evolutionarily
conserved process that is essential for survival. Thermosensing is impaired in various pain …
conserved process that is essential for survival. Thermosensing is impaired in various pain …
An improved conflict avoidance assay reveals modality-specific differences in pain hypersensitivity across sexes
Abnormal encoding of somatosensory modalities (ie, mechanical, cold, and heat) are a
critical part of pathological pain states. Detailed phenotyping of patients' responses to these …
critical part of pathological pain states. Detailed phenotyping of patients' responses to these …
[HTML][HTML] Experiences and reflections about behavioral pain assays in laboratory animals
A Baamonde, L Menéndez - Journal of Neuroscience Methods, 2023 - Elsevier
Pharmacological assays based on the measurement of nociceptive responses in laboratory
animals are a fundamental tool to assess analgesic strategies. During our experience with …
animals are a fundamental tool to assess analgesic strategies. During our experience with …
Pharmacologically and Genetically Targeting the Metabolism of Nav1. 8 Channels to Reduce Chronic Pain
MK Martin - 2024 - search.proquest.com
Neuropathic pain is a growing issue among the population and most current treatments
have been found to be ineffective. New targets such as Na v 1.8 have been identified as …
have been found to be ineffective. New targets such as Na v 1.8 have been identified as …
Identifying the Function of the NR1C2 Splice Variant via Its Interaction With Magi-2 During Inflammatory Pain
GD Sheehan - 2024 - search.proquest.com
Pain is a sensation caused by potentially injurious stimuli that acts as a warning mechanism
necessary for survival. Pain that lasts beyond an injury, or is of unknown origin, can persist …
necessary for survival. Pain that lasts beyond an injury, or is of unknown origin, can persist …
[PDF][PDF] The impact of morphine on nerve injury recovery and lipid metabolism pathways
S Stokes-Heck - 2023 - prism.ucalgary.ca
Neuropathic pain resulting from peripheral nerve injury is among the most debilitating types
of chronic pain conditions. Opioid medications are often used despite their poor efficacy in …
of chronic pain conditions. Opioid medications are often used despite their poor efficacy in …