Harnessing Microbial Effectors for Macrophage-Mediated Drug Delivery

ADP Van Staden, JG Visser, YSL Powrie, C Smith - ACS omega, 2024 - ACS Publications
Macrophage-based drug delivery systems are promising, but their development is still in its
infancy, with many limitations remaining to be addressed. Our aim was to design a system …

[HTML][HTML] Crosslink among phosphatidylinositol-3 kinase/Akt, PTEN and STAT-5A signaling pathways post liposomal galactomannan hepatocellular carcinoma therapy

RM Abdel-Megeed, SH Abd El-Alim, AF Arafa… - Toxicology reports, 2020 - Elsevier
Liposomal drug-delivery systems (LDDs) provide a promising opportunity to precisely target
organs, improve drug bioavailability and reduce systemic toxicity. On the other hand, PI 3 …

Preclinical Assessment Addressing Intravenous Administration of a [68Ga]Ga-PSMA-617 Microemulsion: Acute In Vivo Toxicity, Tolerability, PET Imaging, and …

V Mandiwana, L Kalombo, R Hayeshi, JR Zeevaart… - Molecules, 2021 - mdpi.com
It has been herein presented that a microemulsion, known to be an effective and safe drug
delivery system following intravenous administration, can be loaded with traces of [68Ga] Ga …

Development and validation of an LC-MS/MS method for the quantification of goserelin in a Pheroid® formulation, in simulated intestinal fluid

J Takyi-Williams, L Erasmus, R Hayeshi… - Journal of Pharmaceutical …, 2020 - Elsevier
The purpose of this reported study was to develop and validate an LC-MS/MS method for the
quantification of goserelin in a Pheroid® formulation simulated intestinal fluid …

Manipulation of macrophage phagocytosis-development of an endogenous delivery system

JG Visser - 2020 - scholar.sun.ac.za
The need to administer more potent antimicrobial drugs is supported by the ever-increasing
incidence of multidrug resistance. Given the (necessary) higher toxicity of these drugs …