Therapeutic potential of α-glucosidase inhibitors in type 2 diabetes mellitus: an evidence-based review

SR Joshi, E Standl, N Tong, P Shah… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Postprandial hyperglycemia (PPHG) contributes to micro-and macro-vascular
complications more than fasting hyperglycemia in patients with type 2 diabetes mellitus. Due …

Type 2 diabetes: where we are today: an overview of disease burden, current treatments, and treatment strategies

RK Campbell - Journal of the American Pharmacists Association, 2009 - Elsevier
Objective To provide an overview of the disease burden and current strategies in the
treatment of patients with type 2 diabetes. Data sources Medline search of all relevant …

Empagliflozin as add-on to metformin plus sulphonylurea in patients with type 2 diabetes

HU Haering, L Merker, AV Christiansen, F Roux… - Diabetes research and …, 2015 - Elsevier
This study investigated the long-term efficacy and safety of empagliflozin as add-on to
metformin plus sulphonylurea in patients with type 2 diabetes mellitus (T2DM). Of 666 …

[HTML][HTML] A systematic review exploring the mechanisms by which citrus bioflavonoid supplementation benefits blood glucose levels and metabolic complications in …

A Gupta, A Jamal, DA Jamil, HA Al-Aubaidy - Diabetes & Metabolic …, 2023 - Elsevier
Background Citrus bioflavonoids are polyphenolic compounds that are derived from citrus
fruits and vegetables. Although they are well known for their powerful antioxidant properties …

Incretin‐based therapies for type 2 diabetes mellitus: current status and future prospects

SR Drab - … : The Journal of Human Pharmacology and Drug …, 2010 - Wiley Online Library
Incretin‐based therapies encompass two new classes of antidiabetic drugs: glucagon‐like
peptide‐1 (GLP‐l) receptor agonists (eg, liraglutide, exenatide, and exenatide long‐acting …

Delay of insulin initiation in patients with type 2 diabetes mellitus inadequately controlled with oral hypoglycemic agents (analysis of patient‐and physician‐related …

SG Kim, NH Kim, BJ Ku, HS Shon… - Journal of Diabetes …, 2017 - Wiley Online Library
Abstract Aims/Introduction To assess the time to initiation of insulin therapy, and concurrently
investigate both patient‐and physician‐related factors associated with delaying insulin …

Insights from the liraglutide clinical development program—the liraglutide effect and action in diabetes (LEAD) studies

JB McGill - Postgraduate medicine, 2009 - Taylor & Francis
Standard therapies for type 2 diabetes often fail to maintain glycemic control over the long
term, in part because they do not target the underlying cause. Current treatments may also …

Early and aggressive initiation of insulin therapy for type 2 diabetes: what is the evidence?

K Niswender - Clinical Diabetology, 2009 - journals.viamedica.pl
Type 2 diabetes is a progressive disease in which beta-cell function continually declines
and eventually fails, ultimately requiring nearly all patients to be placed on insulin therapy …

A review of clinical efficacy and safety of canagliflozin 300 mg in the management of patients with type 2 diabetes mellitus

KMP Kumar, S Ghosh, W Canovatchel… - Indian Journal of …, 2017 - journals.lww.com
Currently available antihyperglycemic agents, despite being effective, provide inadequate
glycemic control and/or are associated with side effects or nonadherence. Canagliflozin, a …

Genetic markers predicting sulphonylurea treatment outcomes in type 2 diabetes patients: current evidence and challenges for clinical implementation

NK Loganadan, HZ Huri, SR Vethakkan… - The pharmacogenomics …, 2016 - nature.com
The clinical response to sulphonylurea, an oral antidiabetic agent often used in combination
with metformin to control blood glucose in type 2 diabetes (T2DM) patients, has been widely …