The acquisition of genetic alterations, clonal evolution, and the tumor microenvironment
promote cancer progression, metastasis and therapy resistance. These events correspond …

Pluripotency of embryonic stem cells (ESCs) and induced pluripotent stem cells is regulated
by a well characterized gene transcription circuitry. The circuitry is assembled by ESC …

With a lifetime risk estimated to be one in eight in industrialized countries, breast cancer is
the most frequent type of cancer among women worldwide. Patients are often treated with …

Head and neck squamous carcinoma (HNSCC) is the sixth most prevalent cancer and one
of the most aggressive malignancies worldwide. Despite continuous efforts to identify …

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common human
malignancy in the world, with high mortality and poor prognosis for patients. Among the risk …

Chemotherapy resistance of breast cancer poses a great challenge to the survival of
patients. During breast cancer treatment, the development of intrinsic and acquired drug …

Cisplatin-based chemotherapy is the standard treatment of choice for head and neck
squamous cell carcinoma (HNSCC). The efficiency of platinum-based therapies is directly …

The immune response to oral bacteria and the subsequent activation of inflammatory
signaling is not only dependent on genetic factors. The importance of so‐called epigenetic …

Mucoepidermoid carcinoma (MEC) represents 10-15% of salivary neoplasms. Due to their
low incidence, it is challenging to conduct clinical trials and develop treatment guidelines …

Endothelial-to-mesenchymal transition (EndMT) is a process in which endothelial cells lose
their properties and transform into fibroblast-like cells. This transition process contributes to …