Work over several decades has laid solid foundations for the advancement of liver cell
therapy. To date liver cell therapy in people has taken the form of hepatocyte transplantation …

Tissue engineering combines cell and molecular biology with materials and mechanical
engineering to replace damaged or diseased organs and tissues. Fibrin is a critical blood …

The loss or failure of an organ or tissue is one of the most frequent, devastating, and costly
problems in human health care. A new field, tissue engineering, applies the principles of …

To date, selective cell transplantation has involved injecting cell suspensions into tissues or
the vascular system. This study describes attaching cell preparations to bioerodable artificial …

Many substances are used in the production of biomaterials: metals (titanium), ceramics
(alumina), synthetic polymers (polyurethanes, silicones, polyglycolic acid (PGA), polylactic …

We have fabricated a hepatic tissue construct using a multilayer photopatterning platform for
embedding cells in hydrogels of complex architecture. We first explored the potential of …

Fulminant hepatic failure (FHF) is defined by the appearance of severe liver injury with
hepatic encephalopathy in a previously healthy person. There are an estimated 2,000 cases …

The limited donor organ supply has led to several bridging techniques to sustain patients
with acute and subacute liver failure. We report here the prospective, controlled trial of …

Tissue engineering is a field that has truly emerged in the last decade. It has brought
together diverse technologies, eg cell culture, polymer chemistry and transplantation. The …

Current therapies for most human genetic diseases are inadequate. In response to the need
for effective treatments, modern molecular genetics is providing tools for an unprecedented …