Proteins are nature's primary building blocks for the construction of sophisticated molecular
machines and dynamic materials, ranging from protein complexes such as photosystem II …

The concept of phase-separation-mediated formation of biomolecular condensates provides
a new framework to understand cellular organization and cooperativity-dependent cellular …

Enzymatic reactions in living cells are highly dynamic but simultaneously tightly regulated.
Enzyme engineers seek to construct multienzyme complexes to prevent intermediate …

Metabolic engineering allows development of microbial strains efficiently producing
chemicals and materials, but it requires much time, effort, and cost to make the strains …

Membraneless organelles formed by liquid–liquid phase separation of proteins or nucleic
acids are involved in diverse biological processes in eukaryotes. However, such cellular …

Bacillus subtilis is the most characterized gram-positive bacterium that has significant
attributes, such as growing well on cheap carbon sources, possessing clear inherited …

Compartmentalization is a ubiquitous building principle in cells, which permits segregation
of biological elements and reactions. The carboxysome is a specialized bacterial organelle …

Cancers that appear pathologically similar often respond differently to the same drug
regimens. Methods to better match patients to drugs are in high demand. We demonstrate a …

Protein nanocages have emerged as promising candidates for enzyme immobilization and
cargo delivery in biotechnology and nanotechnology. Carboxysomes are natural …

Biocatalytic cascades represent an attractive approach for the synthesis of valuable
chemicals. To be competitive with chemical synthesis, cascade reactions need to be …