Methods of assessing vagus nerve activity and reflexes
MW Chapleau, R Sabharwal - Heart failure reviews, 2011 - Springer
The methods used to assess cardiac parasympathetic (cardiovagal) activity and its effects on
the heart in both humans and animal models are reviewed. Heart rate (HR)-based methods …
the heart in both humans and animal models are reviewed. Heart rate (HR)-based methods …
Regulation of heart rate in vertebrates during hypoxia: A comparative overview
Acute exposure to low oxygen (hypoxia) places conflicting demands on the heart. Whilst an
increase in heart rate (tachycardia) may compensate systemic oxygen delivery as arterial …
increase in heart rate (tachycardia) may compensate systemic oxygen delivery as arterial …
Chronic intermittent hypoxia augments chemoreflex control of sympathetic activity: role of the angiotensin II type 1 receptor
Chronic exposure to intermittent hypoxia (CIH) increases carotid sinus nerve activity in
normoxia and in response to acute hypoxia. We hypothesized that CIH augments basal and …
normoxia and in response to acute hypoxia. We hypothesized that CIH augments basal and …
Hypoxia activates nucleus tractus solitarii neurons projecting to the paraventricular nucleus of the hypothalamus
TL King, CM Heesch, CG Clark… - American Journal of …, 2012 - journals.physiology.org
Peripheral chemoreceptor afferent information is sent to the nucleus tractus solitarii (nTS),
integrated, and relayed to other brain regions to alter cardiorespiratory function. The nTS …
integrated, and relayed to other brain regions to alter cardiorespiratory function. The nTS …
Nitric oxide, cardiovascular disease and physical exercise
Arterial hypertension (AH) has a high incidence in the world's population and its etiology is
multifactorial, involving genetic, environmental and psychological factors1, 2. Its prevalence …
multifactorial, involving genetic, environmental and psychological factors1, 2. Its prevalence …
Short‐term sustained hypoxia induces changes in the coupling of sympathetic and respiratory activities in rats
DJA Moraes, LGH Bonagamba… - The Journal of …, 2014 - Wiley Online Library
Key points Hypoxia activates peripheral chemoreceptors producing an increase in breathing
and arterial pressure. In conditions of sustained hypoxia, an increase in ventilation and …
and arterial pressure. In conditions of sustained hypoxia, an increase in ventilation and …
Involvement of l‐glutamate and ATP in the neurotransmission of the sympathoexcitatory component of the chemoreflex in the commissural nucleus tractus solitarii of …
Peripheral chemoreflex activation with potassium cyanide (KCN) in awake rats or in the
working heart–brainstem preparation (WHBP) produces:(a) a sympathoexcitatory/pressor …
working heart–brainstem preparation (WHBP) produces:(a) a sympathoexcitatory/pressor …
Hypoxia activates a neuropeptidergic pathway from the paraventricular nucleus of the hypothalamus to the nucleus tractus solitarii
BC Ruyle, PJ Klutho, CP Baines… - American Journal …, 2018 - journals.physiology.org
The paraventricular nucleus of the hypothalamus (PVN) contributes to both autonomic and
neuroendocrine function. PVN lesion or inhibition blunts cardiorespiratory responses to …
neuroendocrine function. PVN lesion or inhibition blunts cardiorespiratory responses to …
Cardiovascular and respiratory evaluation in adenosine A2A receptor knockout mice submitted to short‐term sustained hypoxia
JR Souza, BH Machado - Experimental Physiology, 2023 - Wiley Online Library
Sustained hypoxia (SH) in mice induces changes in the respiratory pattern and increase in
the parasympathetic tone to the heart. Among adenosine G‐protein‐coupled receptors …
the parasympathetic tone to the heart. Among adenosine G‐protein‐coupled receptors …
Interaction between cardiac sympathetic afferent reflex and chemoreflex is mediated by the NTS AT1 receptors in heart failure
WZ Wang, L Gao, HJ Wang… - American Journal of …, 2008 - journals.physiology.org
Several sympathoexcitatory reflexes, such as the cardiac sympathetic afferent reflex (CSAR)
and arterial chemoreflex, are significantly augmented and contribute to elevated sympathetic …
and arterial chemoreflex, are significantly augmented and contribute to elevated sympathetic …