Photoluminescent nanoparticles for chemical and biological analysis and imaging

WR Algar, M Massey, K Rees, R Higgins… - Chemical …, 2021 - ACS Publications
Research related to the development and application of luminescent nanoparticles (LNPs)
for chemical and biological analysis and imaging is flourishing. Novel materials and new …

Nanomedicines accessible in the market for clinical interventions

V Gadekar, Y Borade, S Kannaujia, K Rajpoot… - Journal of Controlled …, 2021 - Elsevier
Nanomedicines refers to nanotechnology inspired pharmaceutical products often referred to
as 'nanopharmaceuticals.'It has displayed commendable potential in enhancing therapeutic …

Disulfide‐bridged organosilica frameworks: designed, synthesis, redox‐triggered biodegradation, and nanobiomedical applications

X Du, F Kleitz, X Li, H Huang, X Zhang… - Advanced Functional …, 2018 - Wiley Online Library
Over the past few years, silica‐based nanotheranostics have demonstrated their great
potential for nano/biomedical applications. However, the uncontrollable and difficult …

[HTML][HTML] EPR-mediated tumor targeting using ultrasmall-hybrid nanoparticles: From animal to human with theranostic AGuIX nanoparticles

G Bort, F Lux, S Dufort, Y Crémillieux, C Verry… - Theranostics, 2020 - ncbi.nlm.nih.gov
Interest of tumor targeting through EPR effect is still controversial due to intrinsic low
targeting efficacy and rare translation to human cancers. Moreover, due to different reasons …

New insights towards mesoporous silica nanoparticles as a technological platform for chemotherapeutic drugs delivery

RM Sabio, AB Meneguin, TC Ribeiro, RR Silva… - International Journal of …, 2019 - Elsevier
Mesoporous silica nanoparticles (MSNs) displays interesting properties for biomedical
applications such as high chemical stability, large surface area and tunable pores diameters …

Ultrasmall silica nanoparticles in translational biomedical research: overview and outlook

N Singh, S Shi, S Goel - Advanced Drug Delivery Reviews, 2023 - Elsevier
The exemplary progress of silica nanotechnology has attracted extensive attention across a
range of biomedical applications such as diagnostics and imaging, drug delivery, and …

Ultrasmall folate receptor alpha targeted enzymatically cleavable silica nanoparticle drug conjugates augment penetration and therapeutic efficacy in models of …

F Wu, PM Chen, TC Gardinier, MZ Turker… - ACS …, 2022 - ACS Publications
To address the key challenges in the development of next-generation drug delivery systems
(DDS) with desired physicochemical properties to overcome limitations regarding safety, in …

Renal clearable nanocarriers: Overcoming the physiological barriers for precise drug delivery and clearance

C Peng, Y Huang, J Zheng - Journal of Controlled Release, 2020 - Elsevier
Physiological barriers encountered in the clinical translation of cancer nanomedicines
inspire the community to more deeply understand nano-bio interactions in not only tumor …

Targeted melanoma radiotherapy using ultrasmall 177Lu-labeled α-melanocyte stimulating hormone-functionalized core-shell silica nanoparticles

X Zhang, F Chen, MZ Turker, K Ma, P Zanzonico… - Biomaterials, 2020 - Elsevier
Abstract Lutetium-177 (177 Lu) radiolabeled ultrasmall (~ 6 nm dia.) fluorescent core-shell
silica nanoparticles (Cornell prime dots or C′ dots) were developed for improving efficacy …

Nanoparticle-Based Treatment Approaches for Skin Cancer: A Systematic Review

MJ Diaz, N Natarelli, S Aflatooni, SJ Aleman… - Current …, 2023 - mdpi.com
Nanoparticles have shown marked promise as both antineoplastic agents and drug carriers.
Despite strides made in immunomodulation, low success rates and toxicity remain …