HIV infection

LG Bekker, C Beyrer, N Mgodi, SR Lewin… - Nature Reviews …, 2023 - nature.com
The AIDS epidemic has been a global public health issue for more than 40 years and has
resulted in~ 40 million deaths. AIDS is caused by the retrovirus, HIV-1, which is transmitted …

Malaria: the past and the present

J Talapko, I Škrlec, T Alebić, M Jukić, A Včev - Microorganisms, 2019 - mdpi.com
Malaria is a severe disease caused by parasites of the genus Plasmodium, which is
transmitted to humans by a bite of an infected female mosquito of the species Anopheles …

Life expectancy after 2015 of adults with HIV on long-term antiretroviral therapy in Europe and North America: a collaborative analysis of cohort studies

A Trickey, CA Sabin, G Burkholder, H Crane… - The Lancet …, 2023 - thelancet.com
Background The life expectancy of people with HIV taking antiretroviral therapy (ART) has
increased substantially over the past 25 years. Most previous studies of life expectancy were …

Comparison of overall and comorbidity-free life expectancy between insured adults with and without HIV infection, 2000-2016

JL Marcus, WA Leyden, SE Alexeeff… - JAMA network …, 2020 - jamanetwork.com
Importance Antiretroviral therapy (ART) has improved life expectancy for individuals with HIV
infection, but recent data comparing life span and comorbidity-free years by HIV status are …

Mapping HIV prevalence in sub-Saharan Africa between 2000 and 2017

L Dwyer-Lindgren, MA Cork, A Sligar, KM Steuben… - Nature, 2019 - nature.com
HIV/AIDS is a leading cause of disease burden in sub-Saharan Africa. Existing evidence has
demonstrated that there is substantial local variation in the prevalence of HIV; however …

Effect of universal testing and treatment on HIV incidence—HPTN 071 (PopART)

RJ Hayes, D Donnell, S Floyd, N Mandla… - … England Journal of …, 2019 - Mass Medical Soc
Background A universal testing and treatment strategy is a potential approach to reduce the
incidence of human immunodeficiency virus (HIV) infection, yet previous trial results are …

Effectiveness and safety of oral HIV preexposure prophylaxis for all populations

VA Fonner, SL Dalglish, CE Kennedy, R Baggaley… - Aids, 2016 - journals.lww.com
Objective: Preexposure prophylaxis (PrEP) offers a promising new approach to HIV
prevention. This systematic review and meta-analysis evaluated the evidence for use of oral …

Antiretroviral drugs for treatment and prevention of HIV infection in adults: 2016 recommendations of the International Antiviral Society–USA panel

HF Günthard, MS Saag, CA Benson, C Del Rio, JJ Eron… - Jama, 2016 - jamanetwork.com
Importance New data and therapeutic options warrant updated recommendations for the use
of antiretroviral drugs (ARVs) to treat or to prevent HIV infection in adults. Objective To …

Effects of pre-exposure prophylaxis for the prevention of human immunodeficiency virus infection on sexual risk behavior in men who have sex with men: a systematic …

MW Traeger, SE Schroeder, EJ Wright… - Clinical Infectious …, 2018 - academic.oup.com
Background Human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP) is
effective in reducing HIV risk in men who have sex with men (MSM). However, concerns …

Nanotherapeutics for nose-to-brain drug delivery: an approach to bypass the blood brain barrier

D Lee, T Minko - Pharmaceutics, 2021 - mdpi.com
Treatment of neurodegenerative diseases or other central nervous system (CNS) disorders
has always been a significant challenge. The nature of the blood-brain barrier (BBB) limits …