[HTML][HTML] Plant lectin: A promising future anti-tumor drug

EHE Konozy, MEM Osman - Biochimie, 2022 - Elsevier
Since the early discovery of plant lectins at the end of the 19th century, and the finding that
they could agglutinate erythrocytes and precipitate glycans from their solutions, many …

Pull the plug: anti‐angiogenesis potential of natural products in gastrointestinal cancer therapy

Y Ai, Z Zhao, H Wang, X Zhang, W Qin… - Phytotherapy …, 2022 - Wiley Online Library
Gastrointestinal cancer (GIC), including gastric cancer and colorectal cancer, is a common
malignant tumor originating from the gastrointestinal epithelium. Although the pathogenesis …

Purification, Characterization, and Assessment of Antimicrobial Activity and Toxicity of Portulaca elatior Leaf Lectin (PeLL)

SP da Silva, JDF da Silva, CBL da Costa… - Probiotics and …, 2023 - Springer
Lectins are carbohydrate-binding proteins with several bioactivities, including antimicrobial
properties. Portulaca elatior is a species found at Brazilian Caatinga and data on the …

Dioclea violacea lectin inhibits tumorigenesis and tumor angiogenesis in vivo

AV de Melo Bisneto, AS Fernandes, L do Carmo Silva… - Biochimie, 2024 - Elsevier
Dioclea violacea seed mannose-binding lectin (DvL) has attracted considerable attention
because of its interesting biological activities, including antitumor, antioxidant, and anti …

Musa acuminata lectin exerts anti-cancer effects on HeLa and EAC cells via activation of caspase and inhibitions of Akt, Erk, and Jnk pathway expression and …

BK Srinivas, MC Shivamadhu, S Jayarama - International Journal of …, 2021 - Elsevier
In the present study aimed to purify the lectin from the sap of Musa acuminata pseudostem
and elucidate the apoptotic and angiogenic molecular mechanism in both in-vitro and in …

Exploring the astonishing beneficial effects of round gourd (Praecitrullus fistulosus) and plant lectins towards cancer: A comprehensive review

I Jabeen, AB Altemimi, R Rabail, S Kafeel… - International Journal of …, 2024 - Elsevier
Praecitrullus fistulosus, commonly known as round gourd or tinda, is a remarkable source of
bioactive substances like polyphenols, antioxidants, carotene, magnesium, and vitamin C. It …

Oridonin exhibits anti-angiogenic activity in human umbilical vein endothelial cells by inhibiting VEGF-induced VEGFR-2 signaling pathway

JH Jiang, J Pi, JY Cai - Pathology-Research and Practice, 2020 - Elsevier
Oridonin has been found to be a potential anti-angiogenesis agent. However, its functional
targets and the underlying mechanisms are still vague. In vitro studies we found that …

[HTML][HTML] PFL-lectin regulates the expression of apoptosis-related proteins to antecedent apoptosis in A549 and HT29 cells

AK Murugesan, M Sathuvan, A Javee - Advances in Cancer Biology …, 2023 - Elsevier
A potential treatment approach to treat this terminal illness is the mushroom-based lectin
carrier system. It has been hypothesized that lectin-induced apoptotic nature causes …

Lectin as an Anticancer Therapeutic Agent

V Mane, SB Arakera, S Pingle… - Handbook of Research on …, 2022 - igi-global.com
Every year nearly 9.6 million people die from cancer worldwide. One third of cancer deaths
are due to behavioural and dietary risks and lack of physical activity. Lectins are powerful …

Roles of Plant and Fungal Lectins in Cancer Diagnosis and Treatment: A Scoping Review

T Kasapoğlu, E Dere - Uluslararası Bilim Teknoloji ve Tasarım …, 2022 - dergipark.org.tr
Lectins are proteins that possess the carbohydrate-binding property that makes the lectins
can bind and recognize carbohydrate moieties on cancer cells. Lectins trigger various cell …